CYP3A43 Antibody (E-9): sc-393860
- CYP3A43 Antibody (E-9) is a mouse monoclonal IgG2b κ CYP3A43 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 46-79 near the N-terminus of CYP3A43 of human origin
- CYP3A43 Antibody (E-9) is recommended for detection of CYP3A43 of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-CYP3A43 Antibody (E-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CYP3A43 Antibody (E-9). This work is in progress.
CYP3A43 Antibody (E-9) is a mouse monoclonal IgG2b kappa light chain antibody that detects CYP3A43 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-CYP3A43 antibody (E-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CYP3A43, a member of the cytochrome P450 superfamily, plays a crucial role in metabolizing various endogenous and exogenous compounds, including drugs and steroids, thereby influencing pharmacokinetics and drug interactions. Understanding CYP3A43 function is particularly important in personalized medicine, as variations in expression can lead to significant differences in drug metabolism among individuals, potentially affecting therapeutic outcomes and risk of adverse effects. CYP3A43 gene location on chromosome 7 is associated with several genetic disorders, highlighting CYP3A43′s importance not only in pharmacology but also in genetic research.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CYP3A43 Antibody (E-9) References:
- The DNA sequence of human chromosome 7. | Hillier, LW., et al. 2003. Nature. 424: 157-64. PMID: 12853948
- The neurobiology of Williams syndrome: cascading influences of visual system impairment? | Eckert, MA., et al. 2006. Cell Mol Life Sci. 63: 1867-75. PMID: 16810457
- Shwachman-Diamond syndrome. | Shimamura, A. 2006. Semin Hematol. 43: 178-88. PMID: 16822460
- Williams-Beuren syndrome diagnosis using fluorescence in situ hybridization. | Osborne, LR., et al. 2006. Methods Mol Med. 126: 113-28. PMID: 16930009
- Lissencephaly 1 linking to multiple diseases: mental retardation, neurodegeneration, schizophrenia, male sterility, and more. | Reiner, O., et al. 2006. Neuromolecular Med. 8: 547-65. PMID: 17028375
- Structural aberrations of chromosome 7 revealed by a combination of molecular cytogenetic techniques in myeloid malignancies. | Brezinová, J., et al. 2007. Cancer Genet Cytogenet. 173: 10-6. PMID: 17284364
- Therapy-related leukemia and myelodysplasia: susceptibility and incidence. | Leone, G., et al. 2007. Haematologica. 92: 1389-98. PMID: 17768113
- Metabolism of the antipsychotic drug olanzapine by CYP3A43. | Zhao, J., et al. 2022. Xenobiotica. 52: 413-425. PMID: 35582917
- Changes in Alprazolam Metabolism by CYP3A43 Mutants. | Zhao, J., et al. 2022. Biomedicines. 10: PMID: 36551778
- Effects of CYP3A43 Expression on Cell Proliferation and Migration of Lung Adenocarcinoma and Its Clinical Significance. | Wei, QY., et al. 2022. Int J Mol Sci. 24: PMID: 36613552
- Restriction fragment length polymorphism associated with the pro alpha 2(I) gene of human type I procollagen. Application to a family with an autosomal dominant form of osteogenesis imperfecta. | Tsipouras, P., et al. 1983. J Clin Invest. 72: 1262-7. PMID: 6313757
- Molecular anatomy of chromosome 7q deletions in myeloid neoplasms: evidence for multiple critical loci. | Liang, H., et al. 1998. Proc Natl Acad Sci U S A. 95: 3781-5. PMID: 9520444
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CYP3A43 Antibody (E-9) | sc-393860 | 200 µg/ml | $322.00 | |||
CYP3A43 Antibody (E-9) AC | sc-393860 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CYP3A43 Antibody (E-9) HRP | sc-393860 HRP | 200 µg/ml | $322.00 | |||
CYP3A43 Antibody (E-9) FITC | sc-393860 FITC | 200 µg/ml | $336.00 | |||
CYP3A43 Antibody (E-9) PE | sc-393860 PE | 200 µg/ml | $349.00 | |||
CYP3A43 Antibody (E-9) Alexa Fluor® 488 | sc-393860 AF488 | 200 µg/ml | $364.00 | |||
CYP3A43 Antibody (E-9) Alexa Fluor® 546 | sc-393860 AF546 | 200 µg/ml | $364.00 | |||
CYP3A43 Antibody (E-9) Alexa Fluor® 594 | sc-393860 AF594 | 200 µg/ml | $364.00 | |||
CYP3A43 Antibody (E-9) Alexa Fluor® 647 | sc-393860 AF647 | 200 µg/ml | $364.00 | |||
CYP3A43 Antibody (E-9) Alexa Fluor® 680 | sc-393860 AF680 | 200 µg/ml | $364.00 | |||
CYP3A43 Antibody (E-9) Alexa Fluor® 790 | sc-393860 AF790 | 200 µg/ml | $364.00 | |||
CYP3A43 (E-9) Neutralizing Peptide | sc-393860 P | 100 µg/0.5 ml | $69.00 |