CYP3A1 Antibody (4i69): sc-70903
- CYP3A1 Antibody (4i69) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against rat liver cytochrome P450 3A1
- recommended for detection of CYP3A4 of human origin, Cyp3a1 of rat origin, and potentially Cyp3a11 of mouse origin (based on inducibility) by WB and IP; may cross-react with other CYP3A gene family members of mouse, rat and human origin
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CYP3A1 Antibody (4i69) for WB applications. These reagents are now offered in bundles with CYP3A1 Antibody (4i69) (see ordering information below).
CYP3A1 Antibody (4i69) is a mouse monoclonal IgG1 antibody that detects CYP3A1 in mouse, rat, and human samples through western blotting (WB) and immunoprecipitation (IP) applications. CYP3A1, also known as Cyp3a23/3a1, is a member of the cytochrome P450 family of enzymes, which play a crucial role in the metabolism of a wide range of endogenous and exogenous compounds, including drugs and toxins. CYP3A1 is primarily expressed in the liver and small intestine, where CYP3A1 is localized to the endoplasmic reticulum, facilitating function in drug metabolism. CYP3A1′s importance lies in its ability to metabolize various pharmaceuticals, which can significantly influence drug efficacy and toxicity. Additionally, CYP3A1 shares homology with other CYP3A family members, such as CYP3A4 in humans, which undergoes alternative splicing to produce different isoforms, highlighting the evolutionary conservation and functional diversity of this enzyme family. CYP3A1 can be induced by glucocorticoids and certain pharmacological agents, making CYP3A1 a key player in pharmacokinetics and drug interactions. With broad species reactivity and proven applications, anti-CYP3A1 antibody (4i69) is an essential tool for researchers studying drug metabolism and the physiological roles of cytochrome P450 enzymes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CYP3A1 Antibody (4i69) | sc-70903 | 200 µg/ml | $322.00 | |||
CYP3A1 Antibody (4i69): m-IgG Fc BP-HRP Bundle | sc-537196 | 200 µg Ab; 10 µg BP | $361.00 | |||
CYP3A1 Antibody (4i69): m-IgGκ BP-HRP Bundle | sc-534403 | 200 µg Ab; 40 µg BP | $361.00 | |||
CYP3A1 Antibody (4i69): m-IgG1 BP-HRP Bundle | sc-545071 | 200 µg Ab; 20 µg BP | $361.00 |