CYP3A Antibody (H-10): sc-390768
- CYP3A Antibody (H-10) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 398-421 of CYP3A4 of human origin
- recommended for detection of CYP3A4, CYP3A5, CYP3A7 and CYP3A43 of human origin by WB, IP, IF, IHC(P) and ELISA; may cross-react with other CYP3A family members
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CYP3A Antibody (H-10) for WB and IHC(P) applications. These reagents are now offered in bundles with CYP3A Antibody (H-10) (see ordering information below).
CYP3A Antibody (H-10) is a mouse monoclonal IgG1 antibody that detects CYP3A in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). CYP3A, a member of the cytochrome P450 family, plays a crucial role in drug metabolism, being responsible for the biotransformation of over 50% of all clinical drugs, which underscores its importance in pharmacology and toxicology. CYP3A is predominantly located in the liver, gastrointestinal tract, and kidneys, which are key organs involved in drug disposition and metabolism. CYP3A localization in these tissues directly influences the pharmacokinetics of therapeutic agents, affecting their efficacy and safety profiles. The CYP3A gene cluster, which includes CYP3A4, CYP3A5, CYP3A7, and CYP3A43, along with two pseudogenes, is mapped to the gene locus 7q22.1, highlighting its genetic significance. Anti-CYP3A antibody (H-10) enables researchers to gain insights into the expression and regulation of this essential enzyme, facilitating a better understanding of drug interactions and individual variability in drug response.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CYP3A Antibody (H-10) | sc-390768 | 200 µg/ml | $322.00 | |||
CYP3A Antibody (H-10): m-IgG Fc BP-HRP Bundle | sc-538100 | 200 µg Ab; 10 µg BP | $361.00 | |||
CYP3A Antibody (H-10): m-IgGκ BP-HRP Bundle | sc-535643 | 200 µg Ab; 40 µg BP | $361.00 | |||
CYP3A Antibody (H-10): m-IgG1 BP-HRP Bundle | sc-545523 | 200 µg Ab; 20 µg BP | $361.00 | |||
CYP3A (H-10) Neutralizing Peptide | sc-390768 P | 100 µg/0.5 ml | $69.00 |