CYP2U1 Antibody (D-4): sc-393368

CYP2U1 Antibody (D-4) is a mouse monoclonal IgM antibody that detects CYP2U1 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-CYP2U1 antibody (D-4) is available as the non-conjugated form. CYP2U1 is a 544 amino acid protein that plays a crucial role in the metabolism of various long-chain fatty acids, including arachidonic acid and docosahexaenoic acid. CYP2U1 is part of the cytochrome P450 family, which is essential for the biotransformation of a wide range of endogenous and xenobiotic compounds. CYP2U1′s ability to metabolize these fatty acids is particularly important as this process may influence the arachidonic acid signaling pathway, which is vital for numerous physiological processes, including inflammation and neuronal signaling in the cerebellum and thymus. Understanding CYP2U1′s function and metabolic pathways can provide insights into potential roles in health and disease, making CYP2U1 (D-4) antibody a valuable tool for researchers studying these complex biological processes.

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CYP2U1 Antibody (D-4) References:

1. CYP2U1, a novel human thymus- and brain-specific cytochrome P450, catalyzes omega- and (omega-1)-hydroxylation of fatty acids.  |  Chuang, SS., et al. 2004. J Biol Chem. 279: 6305-14. PMID: 14660610
2. Characterization and tissue distribution of a novel human cytochrome P450-CYP2U1.  |  Karlgren, M., et al. 2004. Biochem Biophys Res Commun. 315: 679-85. PMID: 14975754
3. Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues.  |  Choudhary, D., et al. 2005. Arch Biochem Biophys. 436: 50-61. PMID: 15752708
4. Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis.  |  Kumarakulasingham, M., et al. 2005. Clin Cancer Res. 11: 3758-65. PMID: 15897573
5. Novel extrahepatic cytochrome P450s.  |  Karlgren, M., et al. 2005. Toxicol Appl Pharmacol. 207: 57-61. PMID: 15987645
6. The human genome project and novel aspects of cytochrome P450 research.  |  Ingelman-Sundberg, M. 2005. Toxicol Appl Pharmacol. 207: 52-6. PMID: 15993453
7. Mutations in CYP2U1, DDHD2 and GBA2 genes are rare causes of complicated forms of hereditary spastic paraparesis.  |  Citterio, A., et al. 2014. J Neurol. 261: 373-81. PMID: 24337409
8. Cytochrome P450 2U1, a very peculiar member of the human P450s family.  |  Dhers, L., et al. 2017. Cell Mol Life Sci. 74: 1859-1869. PMID: 28083596
9. An atypical case of SPG56/CYP2U1-related spastic paraplegia presenting with delayed myelination.  |  Minase, G., et al. 2017. J Hum Genet. 62: 997-1000. PMID: 28725025
10. Cytochrome P450 2U1 Is a Novel Independent Prognostic Biomarker in Breast Cancer Patients.  |  Luo, B., et al. 2020. Front Oncol. 10: 1379. PMID: 32850442
11. Comprehensive analysis of arachidonic acid metabolism-related genes in diagnosis and synovial immune in osteoarthritis: based on bulk and single-cell RNA sequencing data.  |  Tu, B., et al. 2023. Inflamm Res. 72: 955-970. PMID: 36995411
12. Characterization of the Retinal Phenotype Using Multimodal Imaging in Novel Compound Heterozygote Variants of CYP2U1.  |  Sallo, FB., et al. 2025. Ophthalmol Sci. 5: 100618. PMID: 39605873

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-CYP2U1 Antibody (D-4) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-CYP2U1 Antibody (D-4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

CYP2U1 Antibody (D-4) Specifications

Alternate Product Name: CYP2U1

Product Clone Name: D-4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 9-28

Epitope Target: CYP2U1

Epitope Species: human

Product Reactivity/Detection: CYP2U1

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for CYP2U1 Antibody (D-4): P: Blocking Peptide

The preferred CYP2U1 antibody is CYP2U1 Antibody (B-5): sc-393071.