CYP2C6 Antibody (213xB12C6): sc-73484
- CYP2C6 Antibody (213xB12C6) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against CYP2C6 purified from rat liver
- recommended for detection of CYP2C9 and other CYP2C proteins of human origin, phenobarbital-induced CYP2C proteins of mouse origin, and CYP2C6 of rat origin by WB, IP, IF, IHC(P) and ELISA; non cross-reactive with CYP2C8
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CYP2C6 Antibody (213xB12C6) for WB and IHC(P) applications. These reagents are now offered in bundles with CYP2C6 Antibody (213xB12C6) (see ordering information below).
CYP2C6 Antibody (213xB12C6) is a mouse monoclonal IgG1 antibody that detects CYP2C6 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). CYP2C6 is a crucial member of the cytochrome P450 family, which plays a significant role in the oxidation of numerous therapeutic agents, steroids, fatty acids, and other endogenous substances. CYP2C6 is primarily located in the liver, where CYP2C6 is involved in the metabolism of a wide range of therapeutic drugs, including warfarin, mephenytoin, and omeprazole, making CYP2C6 essential for drug detoxification and the synthesis of cholesterol and lipids. CYP2C6 expression is notably inducible by phenobarbital in differentiated Reuber hepatoma cells, which highlights CYP2C6′s importance in hepatic drug metabolism. Understanding the function and regulation of CYP2C6 is vital, as variations in CYP2C6 activity can significantly influence drug efficacy and toxicity, thereby impacting therapeutic outcomes in clinical settings. Anti-CYP2C6 antibody (213xB12C6) provides a reliable tool for researchers studying the intricate mechanisms of drug metabolism and the physiological roles of cytochrome P450 enzymes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CYP2C6 Antibody (213xB12C6) | sc-73484 | 200 µg/ml | $322.00 | |||
CYP2C6 Antibody (213xB12C6): m-IgG Fc BP-HRP Bundle | sc-539486 | 200 µg Ab; 10 µg BP | $361.00 | |||
CYP2C6 Antibody (213xB12C6): m-IgG1 BP-HRP Bundle | sc-541516 | 200 µg Ab; 20 µg BP | $361.00 |