CYP1A2 Antibody (3B8C1): sc-53614
- CYP1A2 Antibody (3B8C1) is a mouse monoclonal IgG1 κ CYP1A2 antibody, cited in 28 publications, provided at 200 µg/ml
- raised against cytochrome P450 protein of rat origin
- CYP1A2 Antibody (3B8C1) is recommended for detection of CYP1A2 of mouse, rat and human origin by WB, IP, IF and IHC(P)
- Anti-CYP1A2 Antibody (3B8C1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CYP1A2 Antibody (3B8C1) for WB and IHC(P) applications. These reagents are now offered in bundles with CYP1A2 Antibody (3B8C1) (see ordering information below).
CYP1A2 Antibody (3B8C1) is a mouse monoclonal IgG1 kappa light chain antibody that detects CYP1A2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Anti-CYP1A2 antibody (3B8C1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CYP1A2, also known as Cytochrome P450 1A2, is a crucial heme-thiolate monooxygenase enzyme that plays a significant role in the NADPH-dependent electron transport pathway within liver microsomes. As a member of the cytochrome P450 family, CYP1A2 is responsible for oxidizing various substrates, including fatty acids, steroids, and xenobiotics, which is vital for drug metabolism and detoxification processes. CYP1A2 metabolizes several clinically important drugs, such as imipramine, propranolol, and clozapine, highlighting its importance in pharmacokinetics and personalized medicine. CYP1A2 is localized to the endoplasmic reticulum membrane, where compounds like 3-methylcholanthrene, insulin, modafinil, and hyperforin induce expression, while fluoroquinolone antibiotics, caffeine, fluvoxamine, and cimetidine can inhibit activity. CYP1A2′s role in estrogen metabolism has been linked to reduced breast cancer risk, underscoring its significance in both drug metabolism and cancer research.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CYP1A2 Antibody (3B8C1) | sc-53614 | 200 µg/ml | $322.00 | |||
CYP1A2 Antibody (3B8C1): m-IgG Fc BP-HRP Bundle | sc-526835 | 200 µg Ab; 10 µg BP | $361.00 | |||
CYP1A2 Antibody (3B8C1): m-IgG1 BP-HRP Bundle | sc-532208 | 200 µg Ab; 20 µg BP | $361.00 | |||
CYP1A2 Antibody (3B8C1) AC | sc-53614 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CYP1A2 Antibody (3B8C1) HRP | sc-53614 HRP | 200 µg/ml | $322.00 | |||
CYP1A2 Antibody (3B8C1) FITC | sc-53614 FITC | 200 µg/ml | $336.00 | |||
CYP1A2 Antibody (3B8C1) PE | sc-53614 PE | 200 µg/ml | $349.00 | |||
CYP1A2 Antibody (3B8C1) Alexa Fluor® 488 | sc-53614 AF488 | 200 µg/ml | $364.00 | |||
CYP1A2 Antibody (3B8C1) Alexa Fluor® 546 | sc-53614 AF546 | 200 µg/ml | $364.00 | |||
CYP1A2 Antibody (3B8C1) Alexa Fluor® 594 | sc-53614 AF594 | 200 µg/ml | $364.00 | |||
CYP1A2 Antibody (3B8C1) Alexa Fluor® 647 | sc-53614 AF647 | 200 µg/ml | $364.00 | |||
CYP1A2 Antibody (3B8C1) Alexa Fluor® 680 | sc-53614 AF680 | 200 µg/ml | $364.00 | |||
CYP1A2 Antibody (3B8C1) Alexa Fluor® 790 | sc-53614 AF790 | 200 µg/ml | $364.00 |