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CYP1A1 Antibody (B-2): sc-48432

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Datasheets
  • CYP1A1 Antibody (B-2) is a mouse monoclonal IgG1 κ, cited in 10 publications, provided at 200 µg/ml
  • raised against amino acids 246-315 of CYP1A1 of human origin
  • recommended for detection of CYP1A1 of mouse, rat and human origin by WB, IP, IF and ELISA
  • See CYP1A1 (A-9): sc-393979 for CYP1A1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CYP1A1 Antibody (B-2). This work is in progress.
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CYP1A1 Antibody (B-2) is a mouse monoclonal IgG1 antibody that detects CYP1A1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CYP1A1 plays a crucial role in the metabolism of various xenobiotic compounds, including polycyclic aromatic hydrocarbons and certain drugs, making CYP1A1 essential for detoxification processes in the body. CYP1A1 is primarily located in the endoplasmic reticulum, where CYP1A1 catalyzes the oxidation of substrates, thereby influencing the bioactivation and detoxification of potentially harmful compounds. Proper functioning of CYP1A1 is vital for maintaining cellular homeostasis and protecting against toxic insults, as dysregulation can lead to adverse effects, including increased susceptibility to carcinogenesis. Anti-CYP1A1 antibody (B-2) provides reliable detection and quantification of CYP1A1, facilitating research into drug metabolism and toxicology.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

CYP1A1 Antibody (B-2)

sc-48432
200 µg/ml
$322.00

Is there any intercross between cyp1a1 and cyp1a2 by western blot in mouse?

Asked by: Anonymous
Thank you for your question. This CYP1A1 (B-2) antibody, sc-48432, is specific for cyp1a1 and will not detect cyp1a2 in a Western blot.
Answered by: Tech Service
Date published: 2019-10-29

I need to use an antibody to detect the protein in samples of avian origin. Do you know if sc-48432: CYP1A1 (B-2) mouse monoclonal antibody will work?

Asked by: Dr Ninau Qelp
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2017-03-06
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Rated 5 out of 5 by from Good WB antibody in normal human epidermalGood WB antibody in normal human epidermal keratinocytes (NHEKs). -SCBT Publication Review
Date published: 2015-05-12
Rated 5 out of 5 by from Good staining in IF in human synovial tissueGood staining in IF in human synovial tissue. -SCBT Publication Review
Date published: 2015-04-26
Rated 5 out of 5 by from Strong band in WB in human recombinant CYP1A1Strong band in WB in human recombinant CYP1A1 fusion protein. -SCBT QC
Date published: 2015-01-24
Rated 5 out of 5 by from Works well in IF in human induced pluripotentWorks well in IF in human induced pluripotent stem cells. -SCBT Publication Review
Date published: 2013-11-17
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CYP1A1 Antibody (B-2) is rated 5.0 out of 5 by 4.
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