cyclin D2 Antibody (DCS-5): sc-53637
- cyclin D2 Antibody (DCS-5) is a mouse monoclonal IgG2b κ, cited in 12 publications, provided at 200 µg/ml
- raised against full length cyclin D2 of human origin
- Anti-cyclin D2 Antibody (DCS-5) is recommended for detection of cyclin D2 of mouse, rat and human origin by WB, IP, IF, FCM and ELISA
- Anti-cyclin D2 Antibody (DCS-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for cyclin D2 Antibody (DCS-5) for WB applications. These reagents are now offered in bundles with cyclin D2 Antibody (DCS-5) (see ordering information below).
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Cyclin D2 Antibody (DCS-5) is a mouse monoclonal IgG2b kappa light chain antibody designed to detect cyclin D2, a pivotal protein involved in regulating the cell cycle. The cyclin D2 protein is characterized by its conserved cyclin box domain, which is essential for binding to cyclin-dependent kinases (Cdk4 and Cdk6), forming active complexes that phosphorylate the retinoblastoma (Rb) protein. This phosphorylation is crucial for the release of E2F transcription factors, facilitating the transition from the G1 phase to the S phase of the cell cycle, thereby promoting DNA synthesis and cell proliferation. The structural integrity of cyclin D2 is vital for its interaction with CDKs and its role in cell cycle progression, making cyclin D2 a key factor in normal cellular growth and a significant contributor to oncogenesis when dysregulated. Anti-cyclin D2 antibody (DCS-5) is raised against the full-length human cyclin D2 protein and demonstrates robust reactivity across mouse, rat, and human species in applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Available in both non-conjugated form and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, cyclin D2 (DCS-5) antibody provides versatility for diverse research applications. By enabling precise detection and analysis of cyclin D2′s structural and functional roles within the cell, cyclin D2 monoclonal antibody (DCS-5) supports advanced studies in cell cycle regulation and the molecular mechanisms underlying cancer development, making cyclin D2 (DCS-5) antibody an invaluable tool for researchers in the field of oncology and cell biology.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cyclin D2 Antibody (DCS-5) | sc-53637 | 200 µg/ml | $322.00 | |||
cyclin D2 Antibody (DCS-5): m-IgG Fc BP-HRP Bundle | sc-525615 | 200 µg Ab; 10 µg BP | $361.00 | |||
cyclin D2 Antibody (DCS-5): m-IgG2b BP-HRP Bundle | sc-549594 | 200 µg Ab; 10 µg BP | $361.00 | |||
cyclin D2 Antibody (DCS-5) AC | sc-53637 AC | 500 µg/ml, 25% agarose | $424.00 | |||
cyclin D2 Antibody (DCS-5) HRP | sc-53637 HRP | 200 µg/ml | $322.00 | |||
cyclin D2 Antibody (DCS-5) FITC | sc-53637 FITC | 200 µg/ml | $336.00 | |||
cyclin D2 Antibody (DCS-5) PE | sc-53637 PE | 200 µg/ml | $349.00 | |||
cyclin D2 Antibody (DCS-5) Alexa Fluor® 488 | sc-53637 AF488 | 200 µg/ml | $364.00 | |||
cyclin D2 Antibody (DCS-5) Alexa Fluor® 546 | sc-53637 AF546 | 200 µg/ml | $364.00 | |||
cyclin D2 Antibody (DCS-5) Alexa Fluor® 594 | sc-53637 AF594 | 200 µg/ml | $364.00 | |||
cyclin D2 Antibody (DCS-5) Alexa Fluor® 647 | sc-53637 AF647 | 200 µg/ml | $364.00 | |||
cyclin D2 Antibody (DCS-5) Alexa Fluor® 680 | sc-53637 AF680 | 200 µg/ml | $364.00 | |||
cyclin D2 Antibody (DCS-5) Alexa Fluor® 790 | sc-53637 AF790 | 200 µg/ml | $364.00 |