cyclin B Antibody (D-5): sc-133183
- cyclin B Antibody (D-5) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against amino acids 1-300 of cyclin B of Drosophila melanogaster origin
- recommended for detection of cyclin B of d origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for cyclin B Antibody (D-5) for WB applications. These reagents are now offered in bundles with cyclin B Antibody (D-5) (see ordering information below).
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Cyclin B Antibody (D-5) is a mouse monoclonal IgG2b antibody that detects cyclin B in Drosophila melanogaster by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Cyclin B is a crucial regulatory protein that plays a significant role in the cell cycle, particularly in the transition from G2 phase to mitosis. Cyclin B binds and activates cyclin-dependent kinase 1 (Cdk1), which is essential for mitosis initiation. Timely regulation of cyclin B levels is vital, as cyclin B accumulation leads to Cdk1 activation, triggering events necessary for cell division. Cyclin B expression peaks during prophase and remains elevated until metaphase, ensuring proper cell preparation for mitosis. Precise control of cyclin B and Cdk1 interaction is critical for maintaining genomic stability and preventing uncontrolled cell proliferation, which can lead to cancer. Anti-cyclin B antibody (D-5) is an invaluable tool for researchers studying cell cycle dynamics and molecular mechanisms underlying cell division in Drosophila and other model organisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cyclin B Antibody (D-5) | sc-133183 | 200 µg/ml | $322.00 | |||
cyclin B Antibody (D-5): m-IgG Fc BP-HRP Bundle | sc-539862 | 200 µg Ab; 10 µg BP | $361.00 | |||
cyclin B Antibody (D-5): m-IgG2b BP-HRP Bundle | sc-549752 | 200 µg Ab; 10 µg BP | $361.00 |