cyclin A Antibody (25): sc-136253
- cyclin A Antibody (25) is a mouse monoclonal IgG1, cited in 3 publications, provided at 50 µg/0.5 ml
- raised against amino acids 26-144 of cyclin A of human origin
- recommended for detection of cyclin A of human origin by WB, IP and IF
- See cyclin A (B-8): sc-271682 for cyclin A antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for cyclin A Antibody (25). This work is in progress.
Cyclin A Antibody (25) is a mouse monoclonal IgG1 antibody that detects cyclin A in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Cyclin A plays a pivotal role in the regulation of the eukaryotic cell cycle, particularly during the transition from the S phase to mitosis, making cyclin A essential for proper cell division and proliferation. Cyclin A is primarily located in the nucleus, where cyclin A associates with cyclin-dependent kinases, particularly Cdk2, to facilitate the progression of the cell cycle. The precise localization of cyclin A is crucial, as cyclin A ensures that the kinase activity is regulated at the right time and place within the cell, preventing uncontrolled cell growth that can lead to tumorigenesis. Cyclin A is also known to interact with various proteins, including the retinoblastoma protein and transcription factors such as E2F, which further underscores cyclin A′s importance in cell cycle control and gene expression regulation. Anti-cyclin A antibody (25) is an invaluable tool for researchers studying cell cycle dynamics, cancer biology, and the intricate signaling pathways that govern cellular proliferation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cyclin A Antibody (25) | sc-136253 | 50 µg/0.5 ml | $316.00 |