CXCL16 Antibody (D-6): sc-376395

CXCL16 Antibody (D-6) is a mouse monoclonal IgG1 antibody that detects CXCL16 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CXCL16, also known as SR-PSOX, plays a crucial role in immune responses by acting as a chemokine that binds to the CXCR6 receptor, which is essential for the recruitment of T cells and other immune cells to sites of inflammation. This interaction not only induces a strong chemotactic response but also triggers calcium mobilization, highlighting CXCL16′s importance in modulating immune cell behavior. CXCL16 is characterized by a unique structure, which includes a transmembrane region and a chemokine domain connected by a mucin-like stalk, resembling the structure of fractalkine. This structural configuration allows CXCL16 to exist in both membrane-bound and soluble forms, facilitating diverse functions in immune signaling. Northern blot analysis has shown that CXCL16 is expressed in various human tissues, including the spleen, lymph nodes, and lungs, with varying levels of expression, underscoring CXCL16′s relevance in both normal physiology and pathological conditions. anti-CXCL16 antibody (D-6) is an invaluable tool for researchers investigating the role of this chemokine in immune responses and related diseases.

The preferred CXCL16 antibody is CXCL16 Antibody (C-5): sc-514363.