Date published: 2025-11-21

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CWF19L1 Antibody (A-8): sc-390017

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Datasheets
  • CWF19L1 Antibody (A-8) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 467-501 near the C-terminus of CWF19L1 of human origin
  • recommended for detection of CWF19L1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
  • m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CWF19L1 Antibody (A-8) for WB applications. These reagents are now offered in bundles with CWF19L1 Antibody (A-8) (see ordering information below).

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    CWF19L1 Antibody (A-8) is a mouse monoclonal IgG1 antibody that detects CWF19L1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CWF19L1, a 538 amino acid protein belonging to the CWF19 family, plays a crucial role in cell cycle regulation and RNA splicing, which are essential processes for maintaining cellular function and genomic stability. CWF19L1 is primarily located in the nucleus, where CWF19L1 participates in the assembly of spliceosomal complexes, thereby influencing the accurate processing of pre-mRNA. This localization is vital because any disruption in RNA splicing can lead to the production of aberrant proteins, potentially resulting in various diseases, including cancer. CWF19L1 is encoded by a gene on human chromosome 10, which is significant as this chromosome harbors numerous genes associated with various genetic disorders. Defects in genes located on chromosome 10 have been linked to conditions such as Charcot-Marie-Tooth disease and multiple endocrine neoplasia type 2, highlighting the importance of studying CWF19L1 and its interactions within the cellular environment. Anti-CWF19L1 antibody (A-8) is an invaluable tool for researchers investigating the intricate mechanisms of cell cycle control and RNA processing.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    CWF19L1 Antibody (A-8)

    sc-390017
    200 µg/ml
    $316.00

    CWF19L1 Antibody (A-8): m-IgG Fc BP-HRP Bundle

    sc-540740
    200 µg Ab; 10 µg BP
    $354.00

    CWF19L1 Antibody (A-8): m-IgG1 BP-HRP Bundle

    sc-542338
    200 µg Ab; 20 µg BP
    $354.00

    CWF19L1 (A-8) Neutralizing Peptide

    sc-390017 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-390017 P appropriate for?

    Asked by: Professor Griffin
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Produced positive Western blot data of CWF19L1Produced positive Western blot data of CWF19L1 expression in non-transfected and mouse CWF19L1 transfected 293T whole cell lysates. -SCBT QC
    Date published: 2014-10-14
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    CWF19L1 Antibody (A-8) is rated 5.0 out of 5 by 1.
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