CstF-77 Antibody (F-3): sc-376553
- CstF-77 Antibody (F-3) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 31-330 mapping near the N-terminus of CstF-77 of human origin
- recommended for detection of CstF-77 of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine, bovine and avian
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CstF-77 Antibody (F-3) for WB applications. These reagents are now offered in bundles with CstF-77 Antibody (F-3) (see ordering information below).
CstF-77 Antibody (F-3) is a mouse monoclonal IgG1 antibody that detects CstF-77 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CstF-77, also known as CstF3, plays a crucial role in the polyadenylation of mRNA precursors, a vital process for gene expression regulation and mRNA stability. CstF-77 is part of the cleavage stimulation factor (CstF) complex, which is essential for the endonucleolytic cleavage of polyadenylation substrates. CstF-77 is highly conserved across eukaryotes and features an α-helical structure with 11 Half-a-TPR-containing (HAT) repeats, which are important for its function in CstF assembly. CstF-77′s ability to form homodimers and interact with other subunits of CstF, namely CstF-64 and CstF-50, underscores its significance in the polyadenylation process. Additionally, CstF-77 interacts with other key factors such as CPSF1 and FCP1, further highlighting CstF-77′s role in the intricate network of protein interactions that govern mRNA processing. anti-CstF-77 antibody (F-3) is an invaluable tool for researchers studying mRNA metabolism and its implications in various biological processes and diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CstF-77 Antibody (F-3) | sc-376553 | 200 µg/ml | $322.00 | |||
CstF-77 Antibody (F-3): m-IgG Fc BP-HRP Bundle | sc-540598 | 200 µg Ab; 10 µg BP | $361.00 | |||
CstF-77 Antibody (F-3): m-IgG1 BP-HRP Bundle | sc-542233 | 200 µg Ab; 20 µg BP | $361.00 |