CstF-50 Antibody (H-8): sc-393317
- CstF-50 Antibody (H-8) is a mouse monoclonal mouse IgG2b κ κ provided at 200 µg/ml
- raised against amino acids 1-300 mapping at the N-terminus of CstF-50 of human origin
- recommended for detection of CstF-50 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CstF-50 Antibody (H-8) for WB applications. These reagents are now offered in bundles with CstF-50 Antibody (H-8) (see ordering information below).
CstF-50 Antibody (H-8) is a mouse monoclonal IgG2b antibody that detects CstF-50 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CstF-50 plays a crucial role in the polyadenylation of mRNA precursors, a vital process for gene expression regulation and mRNA stability. CstF-50 is part of the cleavage stimulation factor (CstF) complex, which is essential for the endonucleolytic cleavage of polyadenylation substrates. CstF-50 shares extensive homology with mammalian G protein beta-subunits and contains a transducin repeat domain, which is a sequence of 44 amino acids repeated seven times. This structural characteristic suggests a potential role in protein-protein interactions, allowing CstF-50 to engage with other polyadenylation and 3′-end cleavage factors, forming a stable complex on pre-mRNA. Such interactions are critical for proper mRNA processing, influencing the overall efficiency of gene expression. Anti-CstF-50 antibody (H-8) is an invaluable tool for researchers studying mRNA processing and its implications in various biological processes and diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CstF-50 Antibody (H-8) | sc-393317 | 200 µg/ml | $322.00 | |||
CstF-50 Antibody (H-8): m-IgG Fc BP-HRP Bundle | sc-538187 | 200 µg Ab; 10 µg BP | $361.00 | |||
CstF-50 Antibody (H-8): m-IgGκ BP-HRP Bundle | sc-535751 | 200 µg Ab; 40 µg BP | $361.00 |