CstF-50 Antibody (G-3): sc-393962
- CstF-50 Antibody (G-3) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 372-397 near the C-terminus of CstF-50 of human origin
- recommended for detection of CstF-50 of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CstF-50 Antibody (G-3) for WB applications. These reagents are now offered in bundles with CstF-50 Antibody (G-3) (see ordering information below).
CstF-50 Antibody (G-3) is a mouse monoclonal IgG1 antibody that detects CstF-50 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CstF-50 plays a crucial role in the polyadenylation of mRNA precursors, a vital process for gene expression regulation and mRNA stability. CstF-50 is part of the cleavage stimulation factor (CstF) complex, which is essential for the endonucleolytic cleavage of polyadenylation substrates. CstF-50 subunit shares extensive homology with mammalian G protein beta-subunits and features a unique transducin repeat domain, consisting of seven repeated 44-amino acid sequences. This structural feature facilitates CstF-50′s interaction with other nuclear proteins, such as BARD1, which associates with BRCA1 and plays a role in inhibiting polyadenylation in vitro. By forming stable complexes with various polyadenylation and 3′-end cleavage factors, CstF-50 is integral to the regulation of mRNA processing, making CstF-50 a key player in maintaining proper gene expression and cellular function.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CstF-50 Antibody (G-3) | sc-393962 | 200 µg/ml | $322.00 | |||
CstF-50 Antibody (G-3): m-IgG Fc BP-HRP Bundle | sc-538346 | 200 µg Ab; 10 µg BP | $361.00 | |||
CstF-50 Antibody (G-3): m-IgGκ BP-HRP Bundle | sc-535939 | 200 µg Ab; 40 µg BP | $361.00 | |||
CstF-50 Antibody (G-3): m-IgG1 BP-HRP Bundle | sc-545654 | 200 µg Ab; 20 µg BP | $361.00 | |||
CstF-50 (G-3) Neutralizing Peptide | sc-393962 P | 100 µg/0.5 ml | $69.00 |