CRYZL1 Antibody (B-7): sc-514537
- CRYZL1 Antibody (B-7) is a mouse monoclonal IgG2b κ CRYZL1 antibody provided at 200 µg/ml
- raised against amino acids 242-312 mapping near the C-terminus of CRYZL1 of human origin
- CRYZL1 Antibody (B-7) is recommended for detection of CRYZL1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-CRYZL1 Antibody (B-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CRYZL1 Antibody (B-7) for WB applications. These reagents are now offered in bundles with CRYZL1 Antibody (B-7) (see ordering information below).
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CRYZL1 Antibody (B-7) is a mouse monoclonal IgG2b kappa light chain antibody that detects CRYZL1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CRYZL1 (B-7) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CRYZL1, also known as ζ-crystallin-like 1, plays a crucial role in maintaining the transparency and refractive index of the eye lens, which is vital for proper vision. CRYZL1 is expressed in various tissues, including heart, brain, skeletal muscle, kidney, pancreas, liver, and lung, indicating potential involvement in diverse physiological processes. CRYZL1 shares a high degree of homology with ζ-crystallin, which is known for NADPH-dependent quinone reductase activity, suggesting CRYZL1 may also participate in redox reactions and cellular stress responses. Expression of CRYZL1 in multiple tissues highlights importance in both lens transparency and broader cellular functions, making CRYZL1 a significant target for research in ocular health and related disorders.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CRYZL1 Antibody (B-7) References:
- Identification of a zeta-crystallin (quinone reductase)-like 1 gene (CRYZL1) mapped to human chromosome 21q22.1. | Kim, MY., et al. 1999. Genomics. 57: 156-9. PMID: 10191096
- Structure of the crystallins. | Slingsby, C. and Clout, NJ. 1999. Eye (Lond). 13 (Pt 3b): 395-402. PMID: 10627816
- Identification of zeta-crystallin/NADPH:quinone reductase as a renal glutaminase mRNA pH response element-binding protein. | Tang, A. and Curthoys, NP. 2001. J Biol Chem. 276: 21375-80. PMID: 11294877
- Alpha-crystallin. | Horwitz, J. 2003. Exp Eye Res. 76: 145-53. PMID: 12565801
- Desminopathies in muscle disease. | Paulin, D., et al. 2004. J Pathol. 204: 418-27. PMID: 15495235
- Transparency and non-refractive functions of crystallins--a proposal. | Bhat, SP. 2004. Exp Eye Res. 79: 809-16. PMID: 15642317
- Lambda-crystallin, a major rabbit lens protein, is related to hydroxyacyl-coenzyme A dehydrogenases. | Mulders, JW., et al. 1988. J Biol Chem. 263: 15462-6. PMID: 3170592
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CRYZL1 Antibody (B-7) | sc-514537 | 200 µg/ml | $322.00 | |||
CRYZL1 Antibody (B-7): m-IgGκ BP-HRP Bundle | sc-524759 | 200 µg Ab, 40 µg BP | $361.00 | |||
CRYZL1 Antibody (B-7): m-IgG2b BP-HRP Bundle | sc-549179 | 200 µg Ab; 10 µg BP | $361.00 | |||
CRYZL1 Antibody (B-7) AC | sc-514537 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CRYZL1 Antibody (B-7) HRP | sc-514537 HRP | 200 µg/ml | $322.00 | |||
CRYZL1 Antibody (B-7) FITC | sc-514537 FITC | 200 µg/ml | $336.00 | |||
CRYZL1 Antibody (B-7) PE | sc-514537 PE | 200 µg/ml | $349.00 | |||
CRYZL1 Antibody (B-7) Alexa Fluor® 488 | sc-514537 AF488 | 200 µg/ml | $364.00 | |||
CRYZL1 Antibody (B-7) Alexa Fluor® 546 | sc-514537 AF546 | 200 µg/ml | $364.00 | |||
CRYZL1 Antibody (B-7) Alexa Fluor® 594 | sc-514537 AF594 | 200 µg/ml | $364.00 | |||
CRYZL1 Antibody (B-7) Alexa Fluor® 647 | sc-514537 AF647 | 200 µg/ml | $364.00 | |||
CRYZL1 Antibody (B-7) Alexa Fluor® 680 | sc-514537 AF680 | 200 µg/ml | $364.00 | |||
CRYZL1 Antibody (B-7) Alexa Fluor® 790 | sc-514537 AF790 | 200 µg/ml | $364.00 |