CRSP34 Antibody (A-2): sc-390295

CRSP34 Antibody (A-2) is a mouse monoclonal IgG1 antibody that recognizes CRSP34 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CRSP34 is a crucial component of the coactivator complex CRSP, which plays a significant role in the regulation of transcription by mediating the interaction between transcriptional activators and RNA polymerase. CRSP34 is primarily located in the nucleus, where CRSP34 is essential for the assembly of transcriptional machinery and the initiation of gene expression. Nuclear localization of CRSP34 underscores CRSP34′s importance in cellular processes, as CRSP34 helps facilitate the transcription of genes vital for various biological functions, including cell growth, differentiation, and response to external signals. Additionally, CRSP34 interacts with other subunits of the CRSP complex, contributing to the overall stability and functionality of the transcriptional coactivator assembly. Anti-CRSP34 antibody (A-2) enables researchers to gain insights into the dynamics of transcription regulation and the intricate networks that govern gene expression in different physiological contexts.

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CRSP34 Antibody (A-2) References:

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4. Energy expenditure during an exercise training session for cardiac patients.  |  Santa-Clara, H., et al. 2018. Appl Physiol Nutr Metab. 43: 292-298. PMID: 29073365
5. Detection rates for adenomas, serrated polyps and clinically relevant serrated polyps can be easily estimated by individually calculated detection rate ratios.  |  Buerger, M., et al. 2020. Scand J Gastroenterol. 55: 745-751. PMID: 32524866
6. QSAR study of unsymmetrical aromatic disulfides as potent avian SARS-CoV main protease inhibitors using quantum chemical descriptors and statistical methods.  |  Chtita, S., et al. 2021. Chemometr Intell Lab Syst. 210: 104266. PMID: 33558778
7. Unsymmetrical aromatic disulfides as SARS-CoV-2 Mpro inhibitors: Molecular docking, molecular dynamics, and ADME scoring investigations.  |  Chtita, S., et al. 2022. J King Saud Univ Sci. 34: 102226. PMID: 35875823
8. Electronic Structure and Magneto-Structural Correlations Study of Cu2UL Trinuclear Schiff Base Complexes: A 3d-5f-3d Case.  |  Meskaldji, S., et al. 2023. J Phys Chem A. 127: 1475-1490. PMID: 36749943
9. Crystal structure and Hirshfeld surface analysis of a new benzimidazole compound, 3-{1-[(2-hy-droxyphen-yl)meth-yl]-1H-1,3-benzo-diazol-2-yl}phenol.  |  Bouhidel, Z., et al. 2024. Acta Crystallogr E Crystallogr Commun. 80: 18-21. PMID: 38312163
10. The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1.  |  Ryu, S., et al. 1999. Nature. 397: 446-50. PMID: 9989412

The preferred CRSP34 antibody is CRSP34 Antibody (B-7): sc-390296.