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CRM1 Antibody (G-9) is a mouse monoclonal IgG3 antibody that detects CRM1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CRM1, also known as exportin 1, plays a crucial role in the nuclear export of proteins and RNA, facilitating the transport of molecules that contain a nuclear export signal (NES) from the nucleus to cytoplasm. This process is vital for maintaining cellular function and regulating gene expression, as CRM1 ensures proteins and RNA are appropriately localized within cells. CRM1′s structure is particularly important, as CRM1 forms a complex with cargo and the small GTPase Ran, which is essential for the export process. The interaction between CRM1 and cargo is highly specific, allowing for selective transport of proteins necessary for various cellular processes, including cell signaling and response to stress. Anti-CRM1 antibody (G-9) enables researchers to gain insights into the dynamics of nuclear-cytoplasmic transport and its implications in cellular health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CRM1 Antibody (G-9) | sc-373865 | 200 µg/ml | $316.00 | |||
CRM1 Antibody (G-9): m-IgGκ BP-HRP Bundle | sc-522536 | 200 µg Ab, 40 µg BP | $354.00 | |||
CRM1 (G-9) Neutralizing Peptide | sc-373865 P | 100 µg/0.5 ml | $68.00 |