CRM1 Antibody (A-7): sc-374124
- CRM1 Antibody (A-7) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1043-1071 at the C-terminus of CRM1 of human origin
- recommended for detection of CRM1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- See CRM1 (C-1): sc-74454 for CRM1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CRM1 Antibody (A-7) for WB and IHC(P) applications. These reagents are now offered in bundles with CRM1 Antibody (A-7) (see ordering information below).
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SEE ALSO...
CRM1 Antibody (A-7) is a mouse monoclonal IgG1 antibody that detects CRM1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). CRM1, also known as exportin 1, plays a crucial role in the nuclear export of proteins and RNA, facilitating the transport of molecules that contain a nuclear export signal. CRM1 (A-7) antibody targets proteins primarily located in the nucleus and cytoplasm, where CRM1 binds to cargo proteins and mediates their translocation through the nuclear pore complex. CRM1′s cellular location enables regulation of protein export timing and efficiency, which is vital for maintaining cellular homeostasis and responding to various stress signals. Dysregulation of CRM1 can lead to protein accumulation in the nucleus, potentially contributing to diseases such as cancer and neurodegenerative disorders. Anti-CRM1 antibody (A-7) serves as an essential tool for researchers studying nuclear transport mechanisms and their implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CRM1 Antibody (A-7) | sc-374124 | 200 µg/ml | $322.00 | |||
CRM1 Antibody (A-7): m-IgG Fc BP-HRP Bundle | sc-537917 | 200 µg Ab; 10 µg BP | $361.00 | |||
CRM1 Antibody (A-7): m-IgGκ BP-HRP Bundle | sc-535390 | 200 µg Ab; 40 µg BP | $361.00 | |||
CRM1 Antibody (A-7): m-IgG1 BP-HRP Bundle | sc-545444 | 200 µg Ab; 20 µg BP | $361.00 | |||
CRM1 (A-7) Neutralizing Peptide | sc-374124 P | 100 µg/0.5 ml | $69.00 |