

Cortistatin Antibody (H-3) is a mouse monoclonal IgG1 light chain antibody that detects cortistatin in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Cortistatin is a 155 amino acid neuropeptide encoded by the human gene CORT, exhibiting strong structural similarity to somatostatin and binding to all known somatostatin receptors. This unique protein plays a crucial role in regulating neuronal activity, particularly by inducing slow-wave sleep, which is essential for maintaining cognitive function and overall health. Cortistatin achieves this by antagonizing the excitatory effects of acetylcholine on the cortex, thereby promoting a state of reduced locomotor activity and facilitating restorative sleep. Additionally, cortistatin activates cation-selective currents that are unresponsive to somatostatin, highlighting its distinct pharmacological properties. Anti-cortistatin antibody (H-3) in various applications makes for an invaluable tool for researchers studying the intricate roles of cortistatin in neurobiology and sleep regulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cortistatin Antibody (H-3) | sc-393107 | 200 µg/ml | $322.00 | |||
cortistatin Antibody (H-3): m-IgG Fc BP-HRP Bundle | sc-538145 | 200 µg Ab; 10 µg BP | $361.00 | |||
cortistatin Antibody (H-3): m-IgGκ BP-HRP Bundle | sc-535705 | 200 µg Ab; 40 µg BP | $361.00 | |||
cortistatin Antibody (H-3): m-IgG1 BP-HRP Bundle | sc-545545 | 200 µg Ab; 20 µg BP | $361.00 |