Coronin 2A Antibody (C-7): sc-376197
- Coronin 2A Antibody (C-7) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 371-480 mapping near the C-terminus of Coronin 2A of human origin
- recommended for detection of Coronin 2A of human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Coronin 2A Antibody (C-7) for WB and IHC(P) applications. These reagents are now offered in bundles with Coronin 2A Antibody (C-7) (see ordering information below).
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Coronin 2A Antibody (C-7) is a mouse monoclonal IgG1 antibody that detects Coronin 2A in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Coronin 2A, also known as CLIPINB, IR10, or WDR2, plays a crucial role in cellular processes by being a key component of the approximately 1.5-2 megadalton nuclear receptor corepressor (N-CoR) complex, which consists of 10-12 proteins that recruit histone deacetylases to generate repressive chromatin. This function is vital for regulating gene expression and maintaining cellular homeostasis, as Coronin 2A influences the transcriptional repression of target genes, thereby impacting various biological processes such as cell differentiation and proliferation. The presence of Coronin 2A in the N-CoR complex underscores its importance in modulating the activity of nuclear receptors, which are critical for responding to hormonal signals and regulating metabolic pathways. With an ability to interact with other proteins and influence chromatin structure, Coronin 2A is essential for proper cellular function and development, making anti-Coronin 2A antibody (C-7) a valuable tool for researchers studying these intricate mechanisms in human cells.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Coronin 2A Antibody (C-7) | sc-376197 | 200 µg/ml | $322.00 | |||
Coronin 2A Antibody (C-7): m-IgG Fc BP-HRP Bundle | sc-540526 | 200 µg Ab; 10 µg BP | $361.00 | |||
Coronin 2A Antibody (C-7): m-IgG1 BP-HRP Bundle | sc-542182 | 200 µg Ab; 20 µg BP | $361.00 |