COQ3 Antibody (F-8): sc-376774

COQ3 Antibody (F-8) is a mouse monoclonal IgG1 antibody that detects COQ3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). COQ3, also known as hexaprenyldihydroxybenzoate methyltransferase or DHHB methyltransferase, is a crucial 369 amino acid protein localized in the mitochondrial matrix, where COQ3 plays a vital role in the biosynthesis of coenzyme Q, a key component of the electron transport chain. COQ3′s primary function as a methyltransferase is to catalyze two essential steps in the production of coenzyme Q, which is indispensable for ATP-dependent energy production during aerobic cellular respiration. Proper functioning of COQ3 is critical, as deficiencies in coenzyme Q can lead to a range of mitochondrial disorders, underscoring COQ3′s importance in maintaining cellular energy homeostasis. Anti-COQ3 antibody (F-8) provides a reliable tool for researchers studying mitochondrial function and related metabolic pathways, facilitating advancements in understanding various diseases linked to mitochondrial dysfunction.

The preferred COQ3 antibody is COQ3 Antibody (E-2): sc-377469.