COQ3 Antibody (E-2): sc-377469
- COQ3 Antibody (E-2) is a mouse monoclonal IgG2a κ COQ3 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 148-242 mapping within an internal region of COQ3 of human origin
- COQ3 Antibody (E-2) is recommended for detection of COQ3 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-COQ3 Antibody (E-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for COQ3 Antibody (E-2) for WB applications. These reagents are now offered in bundles with COQ3 Antibody (E-2) (see ordering information below).
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SEE ALSO...
COQ3 Antibody (E-2) is a mouse monoclonal IgG2a kappa light chain antibody that detects COQ3 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). COQ3 (E-2) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Coenzyme Q (COQ), also known as ubiquinone, plays a critical role in the electron transport chain, facilitating aerobic cellular respiration within mitochondria and is vital for ATP-dependent energy production. COQ3 protein, which is a 369 amino acid methyltransferase, is essential for the biosynthesis of coenzyme Q, specifically catalyzing two key steps in its production. Located in the mitochondrial matrix, COQ3′s proper function is crucial for maintaining mitochondrial health and energy metabolism, as deficiencies in coenzyme Q can lead to a range of mitochondrial disorders and impact overall cellular function. Anti-COQ3 antibody (E-2) enables researchers to gain valuable insights into COQ3′s role in cellular energy production and its implications in various diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
COQ3 Antibody (E-2) References:
- Isolation and functional expression of human COQ3, a gene encoding a methyltransferase required for ubiquinone biosynthesis. | Jonassen, T. and Clarke, CF. 2000. J Biol Chem. 275: 12381-7. PMID: 10777520
- Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. | Wiemann, S., et al. 2001. Genome Res. 11: 422-35. PMID: 11230166
- Saccharomyces cerevisiae Coq9 polypeptide is a subunit of the mitochondrial coenzyme Q biosynthetic complex. | Hsieh, EJ., et al. 2007. Arch Biochem Biophys. 463: 19-26. PMID: 17391640
- An association study of 45 folate-related genes in spina bifida: Involvement of cubilin (CUBN) and tRNA aspartic acid methyltransferase 1 (TRDMT1). | Franke, B., et al. 2009. Birth Defects Res A Clin Mol Teratol. 85: 216-26. PMID: 19161160
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
COQ3 Antibody (E-2) | sc-377469 | 200 µg/ml | $316.00 | |||
COQ3 Antibody (E-2): m-IgGκ BP-HRP Bundle | sc-523340 | 200 µg Ab, 40 µg BP | $354.00 | |||
COQ3 Antibody (E-2): m-IgG2a BP-HRP Bundle | sc-546156 | 200 µg Ab; 10 µg BP | $354.00 | |||
COQ3 Antibody (E-2) AC | sc-377469 AC | 500 µg/ml, 25% agarose | $416.00 | |||
COQ3 Antibody (E-2) HRP | sc-377469 HRP | 200 µg/ml | $316.00 | |||
COQ3 Antibody (E-2) FITC | sc-377469 FITC | 200 µg/ml | $330.00 | |||
COQ3 Antibody (E-2) PE | sc-377469 PE | 200 µg/ml | $343.00 | |||
COQ3 Antibody (E-2) Alexa Fluor® 488 | sc-377469 AF488 | 200 µg/ml | $357.00 | |||
COQ3 Antibody (E-2) Alexa Fluor® 546 | sc-377469 AF546 | 200 µg/ml | $357.00 | |||
COQ3 Antibody (E-2) Alexa Fluor® 594 | sc-377469 AF594 | 200 µg/ml | $357.00 | |||
COQ3 Antibody (E-2) Alexa Fluor® 647 | sc-377469 AF647 | 200 µg/ml | $357.00 | |||
COQ3 Antibody (E-2) Alexa Fluor® 680 | sc-377469 AF680 | 200 µg/ml | $357.00 | |||
COQ3 Antibody (E-2) Alexa Fluor® 790 | sc-377469 AF790 | 200 µg/ml | $357.00 |