Anti-COASY Antibody (E-7) is a mouse monoclonal IgG2a (kappa light chain) COASY antibody provided at 200 µg/ml
raised against amino acids 1-300 mapping at the N-terminus of COASY of human origin
Anti-COASY Antibody (E-7) is recommended for detection of COASY of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-COASY Antibody (E-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of COASY (E-7): sc-393812.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
COASY Antibody (E-7) is a high quality monoclonal COASY antibody (also designated COASY antibody) suitable for the detection of the COASY protein of mouse, rat and human origin. COASY Antibody (E-7) is available as both the non-conjugated anti-COASY antibody form, as well as multiple conjugated forms of anti-COASY antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. COASY (coenzyme A synthase), also known as NBP (nucleotide binding protein), DPCK (dephospho-coenzyme A kinase), PPAT (pantetheine-phosphate adenylyltransferase), UKR1 or pOV-2, is a bifunctional enzyme involved in the biosynthesis of coenzyme A (CoA). COASY exhibits both Ppat activity and DPCK activity, catalyzing steps four and five, respectively, of the CoA biosynthetic pathway. Functioning as a widely expressed monomer and induced by phospholipids, COASY localizes to the outer mitochondrial membrane and facilitates the conversion of 4′-phosphopantetheine to dephospho-CoA and the subsequent generation of CoA. CoA is an important molecule in the cell, participating in carbohydrate, amino acid and fatty acid metabolism. It is the predominant acetyl and acyl group carrier and is used as a substrate by approximately 4% of all cellular enzymes. Due to alternative splicing events, an additional isoform of COASY, namely COASY b, is expressed in brain and contains an extra 29 amino acids at the N-terminus.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences