Date published: 2026-1-9

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CNP Antibody (E-1): sc-374042

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Datasheets
  • CNP Antibody (E-1) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • raised against amino acids 1-115 of CNP of human origin
  • recommended for detection of CNP precursor and all active peptides of human origin by WB, IP, IF and ELISA
  • m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CNP Antibody (E-1) for WB applications. These reagents are now offered in bundles with CNP Antibody (E-1) (see ordering information below).

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    CNP Antibody (E-1) is a mouse monoclonal IgG1 antibody that detects C-type natriuretic peptide (CNP) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CNP is primarily expressed in the brain and plays a crucial role in regulating vascular tone and fluid balance, making CNP essential for cardiovascular health. CNP is known for potent vasodilatory effects, which help lower blood pressure and promote natriuresis, the excretion of sodium through urine. The unique 17-residue ring structure of CNP, stabilized by an intramolecular disulfide bond, is critical for biological activity and interaction with specific receptors, including natriuretic peptide receptor B (NPR-B). Understanding the function and regulation of CNP is vital, as dysregulation of CNP can lead to various cardiovascular diseases. Anti-CNP antibody (E-1) is an invaluable tool for researchers studying the physiological and pathological roles of CNP in human health and disease.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    CNP Antibody (E-1)

    sc-374042
    200 µg/ml
    $322.00

    CNP Antibody (E-1): m-IgG Fc BP-HRP Bundle

    sc-540417
    200 µg Ab; 10 µg BP
    $361.00

    CNP Antibody (E-1): m-IgG1 BP-HRP Bundle

    sc-542107
    200 µg Ab; 20 µg BP
    $361.00

    For Western Blot, is it recommended to use denatured or non-denatured conditions with CNP (E-1): sc-374042 monoclonal antibody?

    Asked by: cjMara
    Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
    Answered by: Technical Support
    Date published: 2017-02-27
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    Rated 5 out of 5 by from Produced nice Western blot data of CNP expressionProduced nice Western blot data of CNP expression in non-transfected and human CNP transfected CMV whole cell lysates. -SCBT QC
    Date published: 2013-10-04
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    CNP Antibody (E-1) is rated 5.0 out of 5 by 1.
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