CNOT11 Antibody (H-7): sc-390318
- CNOT11 Antibody (H-7) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 237-251 within an internal region of CNOT11 of human origin
- recommended for detection of CNOT11 of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including canine and avian
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for CNOT11 Antibody (H-7) for WB applications. These reagents are now offered in bundles with CNOT11 Antibody (H-7) (see ordering information below).
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SEE ALSO...
CNOT11 Antibody (H-7) is a mouse monoclonal IgG2a antibody that detects CNOT11 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CNOT11, also known as C40, is a 510 amino acid protein that plays a crucial role in the CCR4-NOT complex, which is essential for regulating gene expression and mRNA degradation. The CCR4-NOT complex maintains cellular homeostasis and influences various biological processes, including transcriptional regulation and RNA processing. CNOT11′s location within the cytoplasm and nucleus allows interaction with other components of the CCR4-NOT complex and participation in mRNA stability and degradation regulation. By modulating specific mRNA levels, CNOT11 helps control gene expression in response to cellular signals, making CNOT11 a key player in processes such as cell differentiation and response to stress. CNOT11 is encoded by a gene located on human chromosome 2q11.2, which is significant as this chromosome is the second largest in the human genome, containing over 1,400 genes that contribute to a wide array of biological functions. anti-CNOT11 antibody (H-7) serves as an invaluable tool for researchers studying gene regulation mechanisms and the role of the CCR4-NOT complex in various physiological and pathological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CNOT11 Antibody (H-7) | sc-390318 | 200 µg/ml | $322.00 | |||
CNOT11 Antibody (H-7): m-IgG Fc BP-HRP Bundle | sc-540785 | 200 µg Ab; 10 µg BP | $361.00 | |||
CNOT11 Antibody (H-7): m-IgG2a BP-HRP Bundle | sc-546957 | 200 µg Ab; 10 µg BP | $361.00 | |||
CNOT11 (H-7) Neutralizing Peptide | sc-390318 P | 100 µg/0.5 ml | $69.00 |