Date published: 2025-11-1

1-800-457-3801

SCBT Portrait Logo
Seach Input

CNIH4 Antibody (Q-14): sc-81857

4.7(3)
Write a reviewAsk a question

Datasheets
  • CNIH4 Antibody (Q-14) is a mouse monoclonal IgG2a κ CNIH4 antibody provided at 100 µg/ml
  • raised against recombinant CNIH4 of human origin
  • recommended for detection of CNIH4 of human origin by WB, IP and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CNIH4 Antibody (Q-14). This work is in progress.

    QUICK LINKS

    SEE ALSO...

    CNIH4 Antibody (Q-14) is a mouse monoclonal IgG2a kappa light chain antibody that detects CNIH4 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-CNIH4 antibody (Q-14) is available as a non-conjugated format. CNIH4, also known as cornichon homolog 4 or HSPC163, is a 139 amino acid multi-pass membrane protein that plays a crucial role in the regulation of AMPA receptor trafficking and function, which is essential for synaptic transmission and plasticity in the nervous system. Proper functioning of CNIH4 is vital for maintaining synaptic integrity and communication between neurons, and dysregulation has been implicated in various neurological disorders. CNIH4 is encoded by a gene located on chromosome 1, the largest human chromosome, which spans approximately 260 million base pairs and contains around 3,000 genes. Given the extensive number of genes on chromosome 1, CNIH4 is associated with a wide range of diseases, including certain cancers and genetic disorders. The importance of CNIH4 in synaptic function highlights potential as a therapeutic target for conditions related to synaptic dysfunction, making CNIH4 monoclonal antibody (Q-14) a valuable tool for researchers studying these critical pathways.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    CNIH4 Antibody (Q-14) References:

    1. Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.  |  Blackwood, DH., et al. 2001. Am J Hum Genet. 69: 428-33. PMID: 11443544
    2. New insights into the evolution of chromosome 1.  |  Weise, A., et al. 2005. Cytogenet Genome Res. 108: 217-22. PMID: 15545733
    3. Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody.  |  McClintock, D., et al. 2006. Proc Natl Acad Sci U S A. 103: 2154-9. PMID: 16461887
    4. Cell biology: ageing nucleus gets out of shape.  |  Lans, H. and Hoeijmakers, JH. 2006. Nature. 440: 32-4. PMID: 16511477
    5. Chromosome 1 abnormalities in multiple myeloma.  |  Marzin, Y., et al. 2006. Anticancer Res. 26: 953-9. PMID: 16619492
    6. Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness.  |  Hennah, W., et al. 2006. Schizophr Bull. 32: 409-16. PMID: 16699061
    7. The DNA sequence and biological annotation of human chromosome 1.  |  Gregory, SG., et al. 2006. Nature. 441: 315-21. PMID: 16710414
    8. Genomic organization of the selectin family of leukocyte adhesion molecules on human and mouse chromosome 1.  |  Watson, ML., et al. 1990. J Exp Med. 172: 263-72. PMID: 1694218
    9. Fibrolamellar carcinomas show overexpression of genes in the RAS, MAPK, PIK3, and xenobiotic degradation pathways.  |  Kannangai, R., et al. 2007. Hum Pathol. 38: 639-44. PMID: 17367606

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    CNIH4 Antibody (Q-14)

    sc-81857
    100 µg/ml
    $333.00

    For Western Blot, is it recommended to use denatured or non-denatured conditions with CNIH4 (Q-14): sc-81857 antibody?

    Asked by: Trav11
    Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
    Answered by: Technical Support
    Date published: 2017-03-27
    • y_2025, m_10, d_15, h_8CST
    • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasquestionsanswers, tq_1
    • loc_en_US, sid_81857, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getContent, 105ms
    • QUESTIONS, PRODUCT
    Rated 5 out of 5 by from Good for Western BlotThis antibody works in human cell line A-431. -SCBT QC
    Date published: 2023-09-14
    Rated 5 out of 5 by from The antibody is pretty good.I only had to try this antibody for denatured western blotting and my result was good. The only issue is that one has to increase dilution to about 1:200.
    Date published: 2020-02-15
    • y_2025, m_10, d_15, h_8
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasreviews, tv_1, tr_2
    • loc_en_US, sid_81857, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getReviews, 9ms
    • REVIEWS, PRODUCT
    CNIH4 Antibody (Q-14) is rated 4.7 out of 5 by 3.
    • y_2025, m_10, d_15, h_8
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasreviews, tv_1, tr_2
    • loc_en_US, sid_81857, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getAggregateRating, 101ms
    • REVIEWS, PRODUCT