Clathrin Heavy Chain/CLTC Antibody (E-11): sc-271253
- Clathrin Heavy Chain/CLTC Antibody (E-11) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1637-1674 at the C-terminus of Clathrin HC of human origin
- recommended for detection of Clathrin HC of mouse, rat, human and origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, porcine and avian
- See Clathrin Heavy Chain/CLTC (TD.1): sc-12734 for Clathrin Heavy Chain/CLTC antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Clathrin Heavy Chain/CLTC Antibody (E-11) for WB and IHC(P) applications. These reagents are now offered in bundles with Clathrin Heavy Chain/CLTC Antibody (E-11) (see ordering information below).
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Clathrin HC Antibody (E-11) is a mouse monoclonal IgG1 antibody that detects Clathrin HC in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Clathrin HC plays a crucial role in endocytosis, facilitating the formation of clathrin-coated vesicles that transport molecules into cells. Clathrin HC is primarily located in the cytoplasm, where anti-Clathrin HC antibody (E-11) can detect basket-like structures around budding vesicles, ensuring efficient internalization of receptor proteins and other cargo. Proper functioning of Clathrin HC maintains cellular homeostasis and regulates signaling pathways, as disruptions can lead to various diseases, including neurodegenerative disorders and cancer. Clathrin HC is composed of three heavy chains and three light chains that non-covalently associate to form a triskelion structure, with the proximal segment of the heavy chain being essential for binding to light chains, thereby stabilizing the overall structure. Clathrin HC monoclonal antibody (E-11) serves as an invaluable tool for researchers studying endocytic pathways and their implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Clathrin Heavy Chain/CLTC Antibody (E-11) | sc-271253 | 200 µg/ml | $322.00 | |||
Clathrin Heavy Chain/CLTC Antibody (E-11): m-IgG Fc BP-HRP Bundle | sc-537598 | 200 µg Ab; 10 µg BP | $361.00 | |||
Clathrin Heavy Chain/CLTC Antibody (E-11): m-IgGκ BP-HRP Bundle | sc-534908 | 200 µg Ab; 40 µg BP | $361.00 | |||
Clathrin Heavy Chain/CLTC Antibody (E-11): m-IgG1 BP-HRP Bundle | sc-545251 | 200 µg Ab; 20 µg BP | $361.00 | |||
Clathrin Heavy Chain/CLTC (E-11) Neutralizing Peptide | sc-271253 P | 100 µg/0.5 ml | $69.00 |