CKR-9 Antibody (CW-2.2.1): sc-47722
- CKR-9 Antibody (CW-2.2.1) is a mouse monoclonal IgG2b κ CKR-9 antibody provided at 200 µg/ml
- raised against murine wildtype thymocytes
- CKR-9 Antibody (CW-2.2.1) is recommended for detection of CKR-9 of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM
- Anti-CKR-9 Antibody (CW-2.2.1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for CKR-9 Antibody (CW-2.2.1) for WB and IHC(P) applications. These reagents are now offered in bundles with CKR-9 Antibody (CW-2.2.1) (see ordering information below).
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SEE ALSO...
CKR-9 Antibody (CW-2.2.1) is a mouse monoclonal IgG2b kappa light chain antibody that detects CKR-9 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). CKR-9 (CW-2.2.1) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CKR-9 protein, also known as GPR-9-6, is a member of the C-C chemokine receptor family, which is characterized by a pair of adjacent cysteine residues and plays a crucial role in the immune response by acting as a receptor for the thymus-expressed chemokine TECK. This receptor is predominantly expressed in T lymphocytes located in the small intestine, highlighting its specialized function in directing immune cells to sites of inflammation in this specific tissue. The unique expression pattern of CKR-9 and its ligand TECK suggests that they are integral to the immune surveillance and response mechanisms within the gastrointestinal tract, making CKR-9 a significant target for studies related to immune regulation and potential therapeutic interventions in inflammatory diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CKR-9 Antibody (CW-2.2.1) References:
- Structure and function of the CC chemokine receptor (CCR) 8. | Napolitano, M. and Santoni, A. 1999. Forum (Genova). 9: 315-24. PMID: 10611408
- Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity. | Kunkel, EJ., et al. 2000. J Exp Med. 192: 761-8. PMID: 10974041
- The role of thymus-expressed chemokine and its receptor CCR9 on lymphocytes in the regional specialization of the mucosal immune system. | Papadakis, KA., et al. 2000. J Immunol. 165: 5069-76. PMID: 11046037
- HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. | Feng, Y., et al. 1996. Science. 272: 872-7. PMID: 8629022
- Identification of a major co-receptor for primary isolates of HIV-1. | Deng, H., et al. 1996. Nature. 381: 661-6. PMID: 8649511
- HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5. | Dragic, T., et al. 1996. Nature. 381: 667-73. PMID: 8649512
- CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1. | Alkhatib, G., et al. 1996. Science. 272: 1955-8. PMID: 8658171
- The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. | Choe, H., et al. 1996. Cell. 85: 1135-48. PMID: 8674119
- Identification of the CC chemokines TARC and macrophage inflammatory protein-1 beta as novel functional ligands for the CCR8 receptor. | Bernardini, G., et al. 1998. Eur J Immunol. 28: 582-8. PMID: 9521068
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CKR-9 Antibody (CW-2.2.1) | sc-47722 | 200 µg/ml | $322.00 | |||
CKR-9 Antibody (CW-2.2.1): m-IgG Fc BP-HRP Bundle | sc-525555 | 200 µg Ab; 10 µg BP | $361.00 | |||
CKR-9 Antibody (CW-2.2.1): m-IgG2b BP-HRP Bundle | sc-549581 | 200 µg Ab; 10 µg BP | $361.00 | |||
CKR-9 Antibody (CW-2.2.1) AC | sc-47722 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CKR-9 Antibody (CW-2.2.1) HRP | sc-47722 HRP | 200 µg/ml | $322.00 | |||
CKR-9 Antibody (CW-2.2.1) FITC | sc-47722 FITC | 200 µg/ml | $336.00 | |||
CKR-9 Antibody (CW-2.2.1) PE | sc-47722 PE | 200 µg/ml | $349.00 | |||
CKR-9 Antibody (CW-2.2.1) Alexa Fluor® 488 | sc-47722 AF488 | 200 µg/ml | $364.00 | |||
CKR-9 Antibody (CW-2.2.1) Alexa Fluor® 546 | sc-47722 AF546 | 200 µg/ml | $364.00 | |||
CKR-9 Antibody (CW-2.2.1) Alexa Fluor® 594 | sc-47722 AF594 | 200 µg/ml | $364.00 | |||
CKR-9 Antibody (CW-2.2.1) Alexa Fluor® 647 | sc-47722 AF647 | 200 µg/ml | $364.00 | |||
CKR-9 Antibody (CW-2.2.1) Alexa Fluor® 680 | sc-47722 AF680 | 200 µg/ml | $364.00 | |||
CKR-9 Antibody (CW-2.2.1) Alexa Fluor® 790 | sc-47722 AF790 | 200 µg/ml | $364.00 |