CHRDL1 Antibody (1D10): sc-517585
- CHRDL1 Antibody (1D10) is a mouse monoclonal IgG1 κ provided at 50 µg/0.5 ml
- raised against recombinant GST-tagged CHRDL1 protein of human origin
- recommended for detection of CHRDL1 of human origin by ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CHRDL1 Antibody (1D10). This work is in progress.
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CHRDL1 Antibody (1D10) is a mouse monoclonal IgG1 antibody that detects CHRDL1 in human samples through enzyme-linked immunosorbent assay (ELISA). CHRDL1, also known as Chordin-like protein 1, VOPT (Ventroptin), or NRLN1 (Neuralin-1), is a 450 amino acid secreted protein characterized by three VWFC domains. CHRDL1 plays a crucial role in central nervous system development by binding to bone morphogenetic protein 4 (BMP-4) and inhibiting BMP-4 interaction with target receptors, thereby antagonizing BMP-4 activity. CHRDL1′s ability to sequester BMP-4 is vital for proper dorsoventral axis formation, embryonic bone development, and angiogenesis, as well as neural stem cell differentiation. Through BMP signaling regulation, CHRDL1 contributes to the intricate balance of signaling pathways necessary for normal embryonic development and tissue patterning. Anti-CHRDL1 antibody (1D10) serves as an essential tool for researchers investigating these developmental processes and underlying mechanisms of various diseases related to dysregulated BMP signaling.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CHRDL1 Antibody (1D10) | sc-517585 | 50 µg/0.5 ml | $316.00 |