Date published: 2025-12-8

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Chr-A Antibody (F-8): sc-376813

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Datasheets
  • Chr-A Antibody (F-8) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 263-301 within an internal region of Chr-A of human origin
  • recommended for detection of Chr-A of human origin by WB, IP, IF and ELISA
  • See Chr-A (C-12): sc-393941 for Chr-A antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Chr-A Antibody (F-8) for WB applications. These reagents are now offered in bundles with Chr-A Antibody (F-8) (see ordering information below).

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    Chr-A Antibody (F-8) is a mouse monoclonal IgG1 antibody that detects chromogranin A (Chr-A) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Chr-A is an acidic glycoprotein predominantly localized within secretory granules of neuroendocrine and endocrine tissues, playing a crucial role in the storage and release of hormones and neuropeptides. Elevated levels of Chr-A are often associated with neuroendocrine tumors, making Chr-A a valuable biomarker for diagnosis and monitoring of these malignancies. Chr-A (F-8) antibody helps researchers study Chr-A′s role as a precursor to several biologically active peptides, including pancreastatin, which regulates insulin and gastric acid secretion, highlighting Chr-A′s importance in metabolic processes. Chr-A′s ability to interact with various proteins, such as carboxypeptidase E, further emphasizes Chr-A′s role in the complex network of neuroendocrine signaling. Anti-Chr-A antibody (F-8) serves as an essential tool for researchers investigating neuroendocrine function and related pathologies.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Chr-A Antibody (F-8)

    sc-376813
    200 µg/ml
    $316.00

    Chr-A Antibody (F-8): m-IgG Fc BP-HRP Bundle

    sc-540650
    200 µg Ab; 10 µg BP
    $354.00

    Chr-A Antibody (F-8): m-IgG1 BP-HRP Bundle

    sc-542269
    200 µg Ab; 20 µg BP
    $354.00

    Chr-A (F-8) Neutralizing Peptide

    sc-376813 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-376813 P appropriate for?

    Asked by: jenniferc
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Great Western blot data of ChrGreat Western blot data of Chr-A expression in non-transfected and human Chr-A transfected 293T whole cell lysates. -SCBT QC
    Date published: 2013-08-30
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    Chr-A Antibody (F-8) is rated 5.0 out of 5 by 1.
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