CDV Antibody (DV2-12): sc-57660

CDV Antibody (DV2-12) is a mouse monoclonal IgG2b antibody that detects CDV protein by western blotting (WB), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). Anti-CDV antibody (DV2-12) is available as a non-conjugated format, providing researchers with a reliable tool for studying canine distemper virus (CDV), a highly infectious and often fatal viral disease affecting dogs and other carnivores. CDV protein plays a crucial role in viral infection of host cells and immune response evasion, making CDV protein a significant target for therapeutic interventions and vaccine development. Understanding CDV protein structure is essential, as specific domains facilitate binding to host cell receptors, allowing viral entry and replication within the host. This interaction leads to widespread infection and subsequent neurological complications, including encephalomyelitis, which is a common cause of death in infected animals. CDV antibody (DV2-12) applications in research can provide insights into CDV infection mechanisms and contribute to developing effective treatments and preventive measures against this devastating disease.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

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CDV Antibody (DV2-12) References:

1. DNA vaccine encoding nucleocapsid and surface proteins of wild type canine distemper virus protects its natural host against distemper.  |  Cherpillod, P., et al. 2000. Vaccine. 18: 2927-36. PMID: 10825593
2. Canine distemper virus in seals.  |  Osterhaus, AD., et al. 1988. Nature. 335: 403-4. PMID: 3419515
3. Canine distemper virus: review of structural and functional modulations in lymphoid tissues.  |  Krakowka, S., et al. 1980. Am J Vet Res. 41: 284-92. PMID: 6989302
4. Demyelination in experimental canine distemper virus infection: immunological, pathologic, and immunohistological studies.  |  Vandevelde, M., et al. 1982. Acta Neuropathol. 56: 285-93. PMID: 7090737
5. Detection of canine distemper virus nucleocapsid protein gene in canine peripheral blood mononuclear cells by RT-PCR.  |  Shin, Y., et al. 1995. J Vet Med Sci. 57: 439-45. PMID: 7548395
6. Aspects of canine distemper virus and measles virus encephalomyelitis.  |  Summers, BA. and Appel, MJ. 1994. Neuropathol Appl Neurobiol. 20: 525-34. PMID: 7898614
7. The neurobiology of canine distemper virus infection.  |  Vandevelde, M. and Zurbriggen, A. 1995. Vet Microbiol. 44: 271-80. PMID: 8588322
8. Canine distemper virus--a morbillivirus in search of new hosts?  |  Harder, TC. and Osterhaus, AD. 1997. Trends Microbiol. 5: 120-4. PMID: 9080611

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-CDV Antibody (DV2-12) has 3 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

CDV Antibody (DV2-12) Specifications

Alternate Product Name: CDV

Product Clone Name: DV2-12

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b

Amino Acids:

Epitope Target: CDV

Epitope Species: CDV

Product Reactivity/Detection: CDV

Species Reactivity/Detection: NSR

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IF, IHC(P)

Vialing Information: Each vial contains 100 µg IgG_2b in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 3 citations in various scientific publications

Available Conjugates/Forms for CDV Antibody (DV2-12): N/A