Cdk5 Antibody (DC 17): sc-249
- Cdk5 Antibody (DC 17) is a mouse monoclonal IgG1 κ, cited in 108 publications, provided at 200 µg/ml
- raised against recombinant full length Cdk5 of human origin
- Cdk5 Antibody (DC 17) is recommended for detection of Cdk5 of mouse, rat, human and Drosophila origin by WB, IP, IF and ELISA
- Anti-Cdk5 Antibody (DC 17) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Cdk5 Antibody (DC 17) for WB applications. This reagent is now offered in a bundle with Cdk5 Antibody (DC 17) (see ordering information below).
Cdk5 Antibody (DC 17) is a mouse monoclonal IgG1 kappa light chain antibody specifically designed to detect cyclin-dependent kinase 5 (Cdk5), also known as PSSALRE, a pivotal protein involved in neuronal development and function. Cdk5 monoclonal antibody (DC 17) is raised against the recombinant full-length human Cdk5 protein and is reactive with Cdk5 from mouse, rat, human, and Drosophila species, making Cdk5 (DC 17) antibody ideal for applications such as western blotting, immunoprecipitation, immunofluorescence, and ELISA. Cdk5 is predominantly localized in the cytoplasm of neurons, where Cdk5 interacts with activator proteins p35 and p39 to regulate essential processes like neuronal migration, synaptic plasticity, and neurotransmitter release. Proper functioning of Cdk5 is crucial for maintaining neuronal structure and connectivity, and Cdk5 dysregulation has been implicated in various neurodegenerative diseases, including Alzheimer′s disease. By phosphorylating key substrates, Cdk5 modulates critical signaling pathways that underpin neuronal connectivity and plasticity, making Cdk5 a significant target for studying both normal neuronal physiology and pathological conditions. Cdk5 monoclonal antibody (DC 17) is available in multiple conjugated forms, including agarose, HRP, PE, FITC, and several Alexa Fluor® conjugates, providing researchers with versatile options to suit diverse experimental needs. Cdk5 (DC 17) antibody enables precise detection and comprehensive study of Cdk5, facilitating advancements in understanding Cdk5′s role in neurobiology and implications in neurological disorders.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cdk5 Antibody (DC 17) | sc-249 | 200 µg/ml | $322.00 | |||
Cdk5 Antibody (DC 17): m-IgG Fc BP-HRP Bundle | sc-551820 | 200 µg Ab; 10 µg BP | $361.00 | |||
Cdk5 Antibody (DC 17) AC | sc-249 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Cdk5 Antibody (DC 17) HRP | sc-249 HRP | 200 µg/ml | $322.00 | |||
Cdk5 Antibody (DC 17) FITC | sc-249 FITC | 200 µg/ml | $336.00 | |||
Cdk5 Antibody (DC 17) PE | sc-249 PE | 200 µg/ml | $349.00 | |||
Cdk5 Antibody (DC 17) Alexa Fluor® 488 | sc-249 AF488 | 200 µg/ml | $364.00 | |||
Cdk5 Antibody (DC 17) Alexa Fluor® 546 | sc-249 AF546 | 200 µg/ml | $364.00 | |||
Cdk5 Antibody (DC 17) Alexa Fluor® 594 | sc-249 AF594 | 200 µg/ml | $364.00 | |||
Cdk5 Antibody (DC 17) Alexa Fluor® 647 | sc-249 AF647 | 200 µg/ml | $364.00 | |||
Cdk5 Antibody (DC 17) Alexa Fluor® 680 | sc-249 AF680 | 200 µg/ml | $364.00 | |||
Cdk5 Antibody (DC 17) Alexa Fluor® 790 | sc-249 AF790 | 200 µg/ml | $364.00 |