Cdc25A Antibody (5H51): sc-70824
- Cdc25A Antibody (5H51) is a mouse monoclonal IgG2a κ, cited in 5 publications, provided at 200 µg/ml
- raised against purified recombinant Cdc25A
- recommended for detection of Cdc25A of mouse, rat and human origin by WB, IP, IF and IHC(P)
- See Cdc25A (F-6): sc-7389 for Cdc25A antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Cdc25A Antibody (5H51) for WB and IHC(P) applications. These reagents are now offered in bundles with Cdc25A Antibody (5H51) (see ordering information below).
Cdc25A Antibody (5H51) is a mouse monoclonal IgG2a antibody that detects Cdc25A in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Cdc25A plays a crucial role in cell cycle regulation, particularly in the transition from G2 phase to mitosis, by acting as a phosphatase that dephosphorylates and activates the cyclin-dependent kinase Cdc2. This activation is essential for the proper progression of mitosis, as it allows the cell to enter the mitotic phase at the right time, ensuring accurate cell division and maintaining genomic stability. Dysregulation of Cdc25A can lead to uncontrolled cell proliferation and is implicated in various cancers, making Cdc25A a significant target for therapeutic intervention. Cdc25A is primarily located in the nucleus, where Cdc25A interacts with other cell cycle regulators, and Cdc25A activity is tightly controlled by phosphorylation and dephosphorylation events. Anti-Cdc25A antibody (5H51) serves as an invaluable tool for researchers studying cell cycle dynamics and the molecular mechanisms underlying cancer progression.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cdc25A Antibody (5H51) | sc-70824 | 200 µg/ml | $322.00 | |||
Cdc25A Antibody (5H51): m-IgGκ BP-HRP Bundle | sc-534400 | 200 µg Ab; 40 µg BP | $361.00 | |||
Cdc25A Antibody (5H51): m-IgG2a BP-HRP Bundle | sc-546188 | 200 µg Ab; 10 µg BP | $361.00 |