Date published: 2026-4-27

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Cdc20 Antibody (AR12): sc-53398

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Datasheets
  • Cdc20 Antibody (AR12) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
  • raised against urea-denatured His6 Cdc20 recombinant protein of human origin
  • recommended for detection of Cdc20 of mouse, rat and human origin by WB, IP, IF and IHC(P)
  • See Cdc20 (E-7): sc-13162 for Cdc20 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Cdc20 Antibody (AR12) for WB and IHC(P) applications. These reagents are now offered in bundles with Cdc20 Antibody (AR12) (see ordering information below).
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Cdc20 Antibody (AR12) is a mouse monoclonal IgG1 antibody that detects Cdc20 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Cdc20 is a crucial regulatory protein that plays a significant role in the cell cycle, particularly in the transition from the G2 phase to mitosis. Anti-Cdc20 antibody (AR12) functions as an activator of the anaphase-promoting complex/cyclosome (APC/C), which is essential for the degradation of cyclins and other proteins that inhibit the progression of the cell cycle. This degradation is vital for the proper timing of mitotic events, ensuring that cells divide accurately and maintain genomic stability. Dysregulation of Cdc20 can lead to various diseases, including cancer, highlighting its importance as a target for therapeutic intervention. Cdc20 monoclonal antibody (AR12) provides a reliable tool for researchers studying cell cycle dynamics and the molecular mechanisms underlying cell division.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cdc20 Antibody (AR12)

sc-53398
200 µg/ml
$322.00

Cdc20 Antibody (AR12): m-IgG Fc BP-HRP Bundle

sc-536954
200 µg Ab; 10 µg BP
$361.00

Cdc20 Antibody (AR12): m-IgGκ BP-HRP Bundle

sc-534131
200 µg Ab; 40 µg BP
$361.00

Cdc20 Antibody (AR12): m-IgG1 BP-HRP Bundle

sc-544920
200 µg Ab; 20 µg BP
$361.00

Can p55 CDC (AR12): sc-53398 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: Germaine
Thank you for your question. Yes, p55 CDC (AR12): sc-53398 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-27
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Rated 4 out of 5 by from Decent WB signal with some background achievedDecent WB signal with some background achieved using HeLa, Nocodazole treated HeLa and Ramos whole cell lysates. -SCBT QC
Date published: 2015-06-25
Rated 4 out of 5 by from Clear immunoperoxidase cytoplasmic stainingClear immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human tonsil tissue. -SCBT QC
Date published: 2015-03-15
Rated 4 out of 5 by from Performs well in WesternPerforms well in Western, good signal with U87MG cells and U373MG. -SCBT Publication Review
Date published: 2015-03-11
Rated 5 out of 5 by from Very favorable WB achieved using 293T wholeVery favorable WB achieved using 293T whole cell lysate. -SCBT QC
Date published: 2015-01-19
Rated 4 out of 5 by from WB publishable data with human U87MG cellsWB publishable data with human U87MG cells and U373MG - SCBT Publication Review
Date published: 2015-01-04
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Cdc20 Antibody (AR12) is rated 4.2 out of 5 by 5.
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