CD96 Antibody (NK92.50.1): sc-53574
- CD96 Antibody (NK92.50.1) is a mouse monoclonal IgG1 κ CD96 antibody provided at 200 µg/ml
- raised against NK92 cells of human origin
- CD96 Antibody (NK92.50.1) is recommended for detection of CD96 of human origin by FCM
- Anti-CD96 Antibody (NK92.50.1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CD96 Antibody (NK92.50.1). These reagents are now offered in bundles with CD96 Antibody (NK92.50.1) (see ordering information below).
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CD96 Antibody (NK92.50.1) is a mouse monoclonal IgG1 kappa light chain antibody that detects CD96 protein of human origin by flow cytometry (FCM). anti-CD96 antibody (NK92.50.1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CD96 protein, also known as T cell surface protein tactile precursor, is a type I membrane protein belonging to the immunoglobulin superfamily. CD96 is encoded by a gene located on chromosome 3q13.13-q13.2 and plays a crucial role in the immune response, particularly during late phases when activated natural killer (NK) and T cells engage in adhesive interactions. CD96 interacts with CD155, facilitating communication between immune cells and potentially influencing lymphocyte activation and proliferation. CD96 expression is upregulated following NK and T cell activation, allowing these cells to effectively target and engage diseased cells in inflamed tissues. Understanding CD96 function is vital, as CD96 is implicated in antigen presentation and lymphocyte activation, making CD96 a significant player in the immune system′s ability to respond to pathogens and tumors. CD96 monoclonal antibody (NK92.50.1) is an essential tool for researchers studying immune responses and cell interactions in human samples.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CD96 Antibody (NK92.50.1) References:
- Identification and molecular cloning of tactile. A novel human T cell activation antigen that is a member of the Ig gene superfamily. | Wang, PL., et al. 1992. J Immunol. 148: 2600-8. PMID: 1313846
- Cutting edge: CD96 (tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155). | Fuchs, A., et al. 2004. J Immunol. 172: 3994-8. PMID: 15034010
- Downregulation of natural killer cell-activating ligand CD155 by human cytomegalovirus UL141. | Tomasec, P., et al. 2005. Nat Immunol. 6: 181-8. PMID: 15640804
- Antibodies TC-12 ('unique') and TH-111 (CD96) characterize T-cell acute lymphoblastic leukemia and a subgroup of acute myeloid leukemia. | Gramatzki, M., et al. 1998. Exp Hematol. 26: 1209-14. PMID: 9845376
- Heterogeneity of T-acute lymphoblastic leukemia (T-ALL) cell lines: suggestion for classification by immunophenotype and T-cell receptor studies. | Burger, R., et al. 1999. Leuk Res. 23: 19-27. PMID: 9933131
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD96 Antibody (NK92.50.1) | sc-53574 | 200 µg/ml | $316.00 | |||
CD96 Antibody (NK92.50.1): m-IgG Fc BP-HRP Bundle | sc-526829 | 200 µg Ab; 10 µg BP | $354.00 | |||
CD96 Antibody (NK92.50.1): m-IgG1 BP-HRP Bundle | sc-532202 | 200 µg Ab; 20 µg BP | $354.00 | |||
CD96 Antibody (NK92.50.1) AC | sc-53574 AC | 500 µg/ml, 25% agarose | $416.00 | |||
CD96 Antibody (NK92.50.1) HRP | sc-53574 HRP | 200 µg/ml | $316.00 | |||
CD96 Antibody (NK92.50.1) FITC | sc-53574 FITC | 200 µg/ml | $330.00 | |||
CD96 Antibody (NK92.50.1) PE | sc-53574 PE | 200 µg/ml | $343.00 | |||
CD96 Antibody (NK92.50.1) Alexa Fluor® 488 | sc-53574 AF488 | 200 µg/ml | $357.00 | |||
CD96 Antibody (NK92.50.1) Alexa Fluor® 546 | sc-53574 AF546 | 200 µg/ml | $357.00 | |||
CD96 Antibody (NK92.50.1) Alexa Fluor® 594 | sc-53574 AF594 | 200 µg/ml | $357.00 | |||
CD96 Antibody (NK92.50.1) Alexa Fluor® 647 | sc-53574 AF647 | 200 µg/ml | $357.00 | |||
CD96 Antibody (NK92.50.1) Alexa Fluor® 680 | sc-53574 AF680 | 200 µg/ml | $357.00 | |||
CD96 Antibody (NK92.50.1) Alexa Fluor® 790 | sc-53574 AF790 | 200 µg/ml | $357.00 |