CD81 Antibody (5A6): sc-23962
- CD81 Antibody (5A6) is a mouse monoclonal IgG1 κ, cited in 127 publications, provided at 200 µg/ml
- raised against OCI-LY8 cells
- Anti-CD81 Antibody (5A6) is recommended for detection of CD81 of mouse, rat and human origin by WB, IP, IF and FCM
- Anti-CD81 Antibody (5A6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CD81 Antibody (5A6) for WB applications. These reagents are now offered in bundles with CD81 Antibody (5A6) (see ordering information below).
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CD81 Antibody (5A6) is a mouse monoclonal IgG1 kappa light chain antibody specifically designed to target CD81 protein, also known as TAPA-1, a prominent member of the tetraspanin family characterized by its four transmembrane domains. CD81 is widely expressed on cells of hematopoietic, neuroectodermal, and mesenchymal origin, where CD81 plays a vital role in cell growth, signal transduction, and the organization of membrane microdomains. CD81 undergoes essential post-translational modifications, including palmitoylation and glycosylation, which are crucial for proper localization, stability, and interactions with other membrane proteins such as CD37, CD53, CD19, CD21, and MHC class II antigens. Anti-CD81 antibody (5A6) was developed using the OCI-LY8 B lymphoma cell line, ensuring effective detection of CD81 in mouse, rat, and human species through applications like western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Available in both conjugated forms, including horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates, and non-conjugated forms, CD81 monoclonal antibody (5A6) provides versatile options for diverse experimental needs. By targeting CD81, researchers can investigate critical processes such as immune cell activation, viral entry mechanisms, and complex signaling pathways that govern cellular functions. Post-translational modifications of CD81 are particularly important for understanding CD81′s role in pathological conditions like cancer metastasis and immune disorders, making anti-CD81 antibody (5A6) an essential tool for both basic and applied research.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD81 Antibody (5A6) | sc-23962 | 200 µg/ml | $322.00 | |||
CD81 Antibody (5A6): m-IgG Fc BP-HRP Bundle | sc-526643 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD81 Antibody (5A6): m-IgG1 BP-HRP Bundle | sc-532016 | 200 µg Ab; 20 µg BP | $361.00 | |||
CD81 Antibody (5A6) AC | sc-23962 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CD81 Antibody (5A6) HRP | sc-23962 HRP | 200 µg/ml | $322.00 | |||
CD81 Antibody (5A6) FITC | sc-23962 FITC | 200 µg/ml | $336.00 | |||
CD81 Antibody (5A6) PE | sc-23962 PE | 200 µg/ml | $349.00 | |||
CD81 Antibody (5A6) Alexa Fluor® 488 | sc-23962 AF488 | 200 µg/ml | $364.00 | |||
CD81 Antibody (5A6) Alexa Fluor® 546 | sc-23962 AF546 | 200 µg/ml | $364.00 | |||
CD81 Antibody (5A6) Alexa Fluor® 594 | sc-23962 AF594 | 200 µg/ml | $364.00 | |||
CD81 Antibody (5A6) Alexa Fluor® 647 | sc-23962 AF647 | 200 µg/ml | $364.00 | |||
CD81 Antibody (5A6) Alexa Fluor® 680 | sc-23962 AF680 | 200 µg/ml | $364.00 | |||
CD81 Antibody (5A6) Alexa Fluor® 790 | sc-23962 AF790 | 200 µg/ml | $364.00 |