CD81 Antibody (1.3.3.22): sc-7637
- CD81 Antibody (1.3.3.22) is a mouse monoclonal IgG1 κ, cited in 151 publications, provided at 200 µg/ml
- raised against human B cell line from Burkitt lymphoma
- Anti-CD81 Antibody (1.3.3.22) is recommended for detection of CD81 of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM
- CD81 Antibody (1.3.3.22) is available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 405 for IF, IHC(P) and FCM
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CD81 Antibody (1.3.3.22) for WB and IHC(P) applications. These reagents are now offered in bundles with CD81 Antibody (1.3.3.22) (see ordering information below).
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CD81 Antibody (1.3.3.22) is a mouse monoclonal IgG1 kappa light chain antibody that specifically targets CD81 protein, also known as TAPA-1, which is a type III transmembrane protein integral to various cellular functions. CD81 is widely expressed on cells of hematopoietic, neuroectodermal, and mesenchymal origin, playing a pivotal role in cell growth, signal transduction, and the formation of multimolecular complexes with proteins such as CD37, CD53, CD19, CD21, and MHC class II antigens. Anti-CD81 antibody (1.3.3.22) was developed using a human B cell line from Burkitt lymphoma, ensuring effective recognition of CD81 across mouse, rat, and human species. CD81 is essential for immune response regulation and cellular communication, making CD81 a critical target for research in immunology, oncology, and cell biology. CD81 monoclonal antibody (1.3.3.22) is recommended for use in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). Anti-CD81 antibody (1.3.3.22) detects CD81 in multiple species and various experimental settings, making this antibody an invaluable tool for scientists investigating signal transduction pathways and interactions within cellular membranes. Additionally, CD81 is implicated in virus entry mechanisms, highlighting CD81′s importance in infectious disease research. Available in both conjugated and non-conjugated forms, CD81 (1.3.3.22) antibody provides flexibility for diverse experimental designs and detection methods.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CD81 Antibody (1.3.3.22) References:
- Differential expression of murine CD81 highlighted by new anti-mouse CD81 monoclonal antibodies. | Maecker, HT., et al. 2000. Hybridoma. 19: 15-22. PMID: 10768837
- In vitro binding of hepatitis C virus to CD81-positive and -negative human cell lines. | Sasaki, M., et al. 2003. J Gastroenterol Hepatol. 18: 74-9. PMID: 12519228
- TAPA-1, the target of an antiproliferative antibody, defines a new family of transmembrane proteins. | Oren, R., et al. 1990. Mol Cell Biol. 10: 4007-15. PMID: 1695320
- The ins and outs of the transmembrane 4 superfamily. | Wright, MD. and Tomlinson, MG. 1994. Immunol Today. 15: 588-94. PMID: 7531445
- The CD19/CR2/TAPA-1 complex of B lymphocytes: linking natural to acquired immunity. | Fearon, DT. and Carter, RH. 1995. Annu Rev Immunol. 13: 127-49. PMID: 7542009
- A role for CD81 in early T cell development. | Boismenu, R., et al. 1996. Science. 271: 198-200. PMID: 8539618
- Transmembrane-4 superfamily proteins CD81 (TAPA-1), CD82, CD63, and CD53 specifically associated with integrin alpha 4 beta 1 (CD49d/CD29). | Mannion, BA., et al. 1996. J Immunol. 157: 2039-47. PMID: 8757325
- Supramolecular complexes of MHC class I, MHC class II, CD20, and tetraspan molecules (CD53, CD81, and CD82) at the surface of a B cell line JY. | Szöllósi, J., et al. 1996. J Immunol. 157: 2939-46. PMID: 8816400
- Regulation of endothelial cell motility by complexes of tetraspan molecules CD81/TAPA-1 and CD151/PETA-3 with alpha3 beta1 integrin localized at endothelial lateral junctions. | Yáñez-Mó, M., et al. 1998. J Cell Biol. 141: 791-804. PMID: 9566977
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD81 Antibody (1.3.3.22) | sc-7637 | 200 µg/ml | $322.00 | |||
CD81 Antibody (1.3.3.22): m-IgG Fc BP-HRP Bundle | sc-526504 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD81 Antibody (1.3.3.22): m-IgG1 BP-HRP Bundle | sc-531877 | 200 µg Ab; 20 µg BP | $361.00 | |||
CD81 Antibody (1.3.3.22) FITC | sc-7637 FITC | 200 µg/ml | $336.00 | |||
CD81 Antibody (1.3.3.22) PE | sc-7637 PE | 200 µg/ml | $349.00 | |||
CD81 Antibody (1.3.3.22) Alexa Fluor® 488 | sc-7637 AF488 | 200 µg/ml | $364.00 | |||
CD81 Antibody (1.3.3.22) Alexa Fluor® 546 | sc-7637 AF546 | 200 µg/ml | $364.00 | |||
CD81 Antibody (1.3.3.22) Alexa Fluor® 594 | sc-7637 AF594 | 200 µg/ml | $364.00 | |||
CD81 Antibody (1.3.3.22) Alexa Fluor® 647 | sc-7637 AF647 | 200 µg/ml | $364.00 | |||
CD81 Antibody (1.3.3.22) Alexa Fluor® 680 | sc-7637 AF680 | 200 µg/ml | $364.00 | |||
CD81 Antibody (1.3.3.22) Alexa Fluor® 790 | sc-7637 AF790 | 200 µg/ml | $364.00 | |||
CD81 Antibody (1.3.3.22) Alexa Fluor® 405 | sc-7637 AF405 | 200 µg/ml | $364.00 |