Date published: 2026-5-17

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CD8-α Antibody (6A242): sc-70802

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Datasheets
  • CD8-α Antibody (6A242) is a mouse monoclonal IgG1 κ, cited in 6 publications, provided at 200 µg/ml
  • raised against thymocyte membrane glycoproteins of rat origin
  • recommended for detection of CD8-α of mouse and rat origin by WB, IP, IF, IHC(P) and FCM
  • available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • also provided azide-free for blocking, sc-70802 L, 200 µg/0.1 ml
  • m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CD8-α Antibody (6A242) for WB and IHC(P) applications. These reagents are now offered in bundles with CD8-α Antibody (6A242) (see ordering information below).
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CD8-α Antibody (6A242) is a mouse monoclonal IgG1 kappa light chain antibody raised against thymocyte membrane glycoproteins of rat origin, designed for the detection of CD8-α in mouse and rat samples via western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). CD8-α, also known as CD8A, Leu2, or p32, is a cell surface glycoprotein predominantly expressed on cytotoxic T lymphocytes and some natural killer cells, forming either homodimers (αα) or heterodimers (αβ) with CD8-β. CD8-α plays a crucial role in the immune system by binding to major histocompatibility complex (MHC) class I molecules on antigen-presenting cells, thereby enhancing antigen recognition by the T cell receptor (TCR) and strengthening T cell-antigen presenting cell interactions. This function is essential for the activation and cytotoxic response of CD8+ T cells against intracellular pathogens and tumor cells. CD8-α is vital for T cell development, selection, and peripheral immune responses, making CD8-α a significant marker in immunological research and diagnostics. Anti-CD8-α antibody (6A242) is a valuable tool for studying T cell-mediated immunity and for the identification and characterization of CD8+ T cell populations in various biological samples.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

CD8-α Antibody (6A242)

sc-70802
200 µg/ml
$322.00

CD8-α Antibody (6A242): m-IgG Fc BP-HRP Bundle

sc-539312
200 µg Ab; 10 µg BP
$361.00

CD8-α Antibody (6A242): m-IgG1 BP-HRP Bundle

sc-541401
200 µg Ab; 20 µg BP
$361.00

CD8-α Antibody (6A242) FITC

sc-70802 FITC
200 µg/ml
$336.00

CD8-α Antibody (6A242) L

sc-70802 L
200 µg/0.1 ml
$322.00

CD8-α Antibody (6A242) PE

sc-70802 PE
200 µg/ml
$349.00

Can CD8-α (6A242): sc-70802 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: Trav11
Thank you for your question. Yes, CD8-α (6A242): sc-70802 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-27
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Rated 4 out of 5 by from Published Flow cytometry data for use inPublished Flow cytometry data for use in mouse lymph nodes and spleen. -SCBT Publication Review
Date published: 2015-01-16
Rated 4 out of 5 by from Positive band seen in WB in rat PBL wholePositive band seen in WB in rat PBL whole cell lysate. -SCBT QC
Date published: 2014-12-11
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CD8-α Antibody (6A242) is rated 4.0 out of 5 by 2.
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