
CD74 Antibody (2X31) is a mouse monoclonal IgG1 antibody that recognizes CD74 in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and flow cytometry (FCM). CD74, also known as the invariant chain, plays a crucial role in the immune system by regulating peptide loading onto major histocompatibility complex class II (MHC II) molecules. This process is vital for proper antigen presentation to T lymphocytes, which is essential for initiating adaptive immune responses. The interaction between CD74 and MHC II occurs during MHC II transport to the endosomal compartment, where peptide binding takes place. CD74 is expressed in various immune cells, particularly in normal B lymphocytes, and CD74 expression is critical for the development and function of these cells. CD74 involvement in immune signaling pathways highlights CD74 importance in maintaining immune homeostasis and responding to pathogens. Anti-CD74 antibody (2X31) serves as an invaluable tool for researchers studying immune responses, antigen presentation, and related cellular processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD74 Antibody (2X31) | sc-70781 | 200 µg/ml | $322.00 | |||
CD74 Antibody (2X31): m-IgG Fc BP-HRP Bundle | sc-539310 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD74 Antibody (2X31): m-IgG1 BP-HRP Bundle | sc-541399 | 200 µg Ab; 20 µg BP | $361.00 |