


CD43 Antibody (OX57) is a mouse monoclonal IgG2b antibody that detects CD43 in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). CD43, also known as leukosialin, is a major O-glycosylated sialoglycoprotein predominantly found on the surface of leukocytes, where CD43 plays a crucial role in cellular adhesion and tumor progression. CD43 is a member of the surface mucin family and is characterized by extensive glycosylation, which is essential for CD43′s function in modulating cell-cell interactions and signaling pathways. The structure of CD43, with a large extracellular domain, allows CD43 to interact with various ligands and receptors, influencing immune responses and the behavior of T cells and certain B cell populations. By acting as a negative regulator of cellular adhesion, CD43 helps maintain the balance between immune activation and inhibition, making CD43 a vital component in the immune system′s ability to respond to pathogens while preventing excessive inflammation. Anti-CD43 antibody (OX57) is an invaluable tool for researchers studying immune cell dynamics and the role of glycoproteins in cellular communication.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD43 Antibody (OX57) | sc-53043 | 200 µg/ml | $322.00 | |||
CD43 Antibody (OX57): m-IgGκ BP-HRP Bundle | sc-534047 | 200 µg Ab; 40 µg BP | $361.00 | |||
CD43 Antibody (OX57): m-IgG2b BP-HRP Bundle | sc-549243 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD43 Antibody (OX57) FITC | sc-53043 FITC | 200 µg/ml | $336.00 | |||
CD43 Antibody (OX57) L | sc-53043 L | 200 µg/0.1 ml | $322.00 | |||
CD43 Antibody (OX57) PE | sc-53043 PE | 200 µg/ml | $349.00 |