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CD42a Antibody (D-6) is a mouse monoclonal IgG1 antibody that detects CD42a in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CD42a is a single-chain membrane glycoprotein that forms a noncovalent complex with CD42b, also known as glycoprotein Ib α (GPIb α), which is composed of α and β chains. The β chain of CD42b is designated as CD42c and is expressed on platelets and megakaryocytes, where both CD42a and CD42b play crucial roles. This complex is a major component of the platelet surface and functions as a receptor for von Willebrand′s factor, facilitating platelet adhesion during hemostasis. The interaction between CD42a and von Willebrand′s factor is vital for the initial stages of blood clot formation, highlighting CD42a′s importance in maintaining vascular integrity and preventing excessive bleeding. Anti-CD42a antibody (D-6) is an essential tool for researchers studying platelet biology and related disorders, providing insights into the mechanisms of thrombosis and hemostatic function.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD42a Antibody (D-6) | sc-390273 | 200 µg/ml | $322.00 | |||
CD42a Antibody (D-6): m-IgG Fc BP-HRP Bundle | sc-540778 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD42a Antibody (D-6): m-IgG1 BP-HRP Bundle | sc-542366 | 200 µg Ab; 20 µg BP | $361.00 |