CD3 Antibody (21-L5): sc-1175
- CD3 Antibody (21-L5) is a mouse monoclonal IgG2a, cited in 4 publications, provided at 200 µg/ml
- recommended for detection of CD3 of human origin by IF and FCM
- available conjugated to FITC for IF, IHC(P) and FCM
- See CD3 (PC3/188A): sc-20047 for CD3 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD3 Antibody (21-L5). This work is in progress.
CD3 Antibody (21-L5) is a mouse monoclonal IgG2a antibody engineered to recognize human CD3, demonstrating robust reactivity in both immunofluorescence (IF) and flow cytometry (FCM) applications. CD3, also known as the T cell co-receptor complex or TCR-CD3 complex, is integral to the T cell receptor (TCR) signaling pathway, which is essential for the activation and regulation of T lymphocytes. CD3 (21-L5) monoclonal antibody targets the CD3 complex, a multisubunit assembly composed of gamma, epsilon, delta, zeta, and eta chains, each playing a critical role in transmitting extracellular antigen recognition into intracellular activation signals. The CD3 complex contains immunoreceptor tyrosine-based activation motifs (ITAMs) that are pivotal for recruiting and activating protein kinases such as ZAP-70 and Syk, thereby initiating downstream signaling cascades necessary for T cell responses. Anti-CD3 antibody (21-L5) facilitates detailed studies of T cell activation, signal transduction, and immune response mechanisms, making CD3 (21-L5) antibody an invaluable tool for immunological research.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD3 Antibody (21-L5) | sc-1175 | 200 µg/ml | $322.00 | |||
CD3 Antibody (21-L5) FITC | sc-1175 FITC | 200 µg/ml | $336.00 |