CD1C Antibody (3H648): sc-70570

CD1C Antibody (3H648) is a mouse monoclonal IgG1 antibody that detects CD1C in human samples through applications such as immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). CD1C is a member of the CD1 multigene family, which encodes glycoproteins that play a crucial role in the immune system by presenting lipid antigens to T lymphocytes. CD1C is primarily located on the surface of antigen-presenting cells, including dendritic cells and B cells, where CD1C facilitates the recognition of lipid-based antigens by T cells, thereby influencing immune responses. Proper localization of CD1C is vital for function, as CD1C ensures that lipid antigens are effectively presented to T cells in the appropriate microenvironment, which is essential for initiating and regulating adaptive immunity. CD1C is involved in the development and activation of CD1-restricted T cells, highlighting CD1C′s importance in both innate and adaptive immune responses. The human CD1 genes, including CD1C, are clustered on chromosome 1q22-23, underscoring their evolutionary relationship and functional interdependence. Anti-CD1C antibody (3H648) is an invaluable tool for researchers studying lipid antigen presentation and T cell activation in human immunology.

The preferred CD1C antibody is CD1C Antibody (B-6): sc-390980.