CD1B Antibody (M-T101): sc-58975
- CD1B Antibody (M-T101) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against thymocytes of human origin
- CD1B Antibody (M-T101) is recommended for detection of CD1B of human origin by IP, IF and FCM
- Anti-CD1B Antibody (M-T101) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CD1B Antibody (M-T101). These reagents are now offered in bundles with CD1B Antibody (M-T101) (see ordering information below).
QUICK LINKS
CD1B Antibody (M-T101) is a mouse monoclonal IgG1 kappa light chain antibody that detects CD1B protein of human origin by immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Anti-CD1B antibody (M-T101) is available in non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CD1B plays a crucial role in the immune system by presenting lipid antigens to T lymphocytes, essential for activating specific immune responses. CD1B protein is part of the CD1 multigene family, including CD1A, CD1C, CD1D, and CD1E, all structurally similar to major histocompatibility complex (MHC) class I molecules. CD1B (M-T101) antibody recognizes CD1B expressed on cortical thymocytes, Langerhans cells, a subset of B cells, and certain dendritic cells, highlighting CD1B′s importance in immune cell interactions. Adaptor-protein complexes and CD1-associated chaperones regulate CD1B trafficking, vital for CD1-restricted T cell development and activation. Constitutive endocytosis of CD1B and differential sorting of MHC class II from lysosomes during dendritic cell maturation ensure effective separation of peptide and lipid antigen-presenting pathways. Human CD1 genes are linked in a cluster at chromosome 1q 22-23, emphasizing their evolutionary relationship and functional importance in the immune system.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD1B Antibody (M-T101) | sc-58975 | 200 µg/ml | $322.00 | |||
CD1B Antibody (M-T101): m-IgG Fc BP-HRP Bundle | sc-526921 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD1B Antibody (M-T101): m-IgG1 BP-HRP Bundle | sc-532294 | 200 µg Ab; 20 µg BP | $361.00 | |||
CD1B Antibody (M-T101) AC | sc-58975 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CD1B Antibody (M-T101) HRP | sc-58975 HRP | 200 µg/ml | $322.00 | |||
CD1B Antibody (M-T101) FITC | sc-58975 FITC | 200 µg/ml | $336.00 | |||
CD1B Antibody (M-T101) PE | sc-58975 PE | 200 µg/ml | $349.00 | |||
CD1B Antibody (M-T101) Alexa Fluor® 488 | sc-58975 AF488 | 200 µg/ml | $364.00 | |||
CD1B Antibody (M-T101) Alexa Fluor® 546 | sc-58975 AF546 | 200 µg/ml | $364.00 | |||
CD1B Antibody (M-T101) Alexa Fluor® 594 | sc-58975 AF594 | 200 µg/ml | $364.00 | |||
CD1B Antibody (M-T101) Alexa Fluor® 647 | sc-58975 AF647 | 200 µg/ml | $364.00 | |||
CD1B Antibody (M-T101) Alexa Fluor® 680 | sc-58975 AF680 | 200 µg/ml | $364.00 | |||
CD1B Antibody (M-T101) Alexa Fluor® 790 | sc-58975 AF790 | 200 µg/ml | $364.00 |