CD19 Antibody (BCE19) is a mouse monoclonal IgG1 antibody that detects CD19 in human samples through immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). CD19 is a crucial transmembrane glycoprotein that plays a significant role in B-cell development and activation, as anti-CD19 antibody (BCE19) selectively recognizes proteins expressed on the surface of B-lymphocytes. CD19 contains two extracellular immunoglobulin-like domains, which are essential for activating intracellular signaling pathways, including the Ras and phosphatidylinositol 3-kinase pathways. CD19 activation leads to the cross-linking of immunoglobulin chains on the membrane, facilitating the association with Src family protein tyrosine kinases, which are vital for downstream signaling events. CD19 is continuously expressed throughout the various stages of B-cell development, including the terminal differentiation into plasma cells, making CD19 (BCE19) monoclonal antibody a reliable marker for identifying B-cells. CD19 forms functional complexes with other B-lymphocyte surface proteins, such as integrin β1, CD21, and CD81, which are integral to regulating B-cell maturation and function. CD19 (BCE19) antibody serves as an invaluable tool for researchers studying B-cell biology and related immunological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD19 Antibody (BCE19) | sc-69736 | 200 µg/ml | $322.00 | |||
CD19 Antibody (BCE19): m-IgG Fc BP-HRP Bundle | sc-539235 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD19 Antibody (BCE19): m-IgG1 BP-HRP Bundle | sc-541343 | 200 µg Ab; 20 µg BP | $361.00 | |||
CD19 Antibody (BCE19) FITC | sc-69736 FITC | 200 µg/ml | $336.00 |