CD155 Antibody (SKII.4): sc-53572
- CD155 Antibody (SKII.4) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against the SK-N-S1 neuroblastoma cell line of human origin
- CD155 Antibody (SKII.4) is recommended for detection of CD155 of human origin by WB, IP and FCM
- Anti-CD155 Antibody (SKII.4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CD155 Antibody (SKII.4) for WB applications. These reagents are now offered in bundles with CD155 Antibody (SKII.4) (see ordering information below).
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CD155 Antibody (SKII.4) is a mouse monoclonal IgG1 kappa light chain antibody that detects CD155 of human origin by western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). Anti-CD155 antibody (SKII.4) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CD155, a crucial member of the immunoglobulin superfamily, serves as the primary receptor for poliovirus, facilitating viral entry into host cells. CD155′s structure contains multiple immunoglobulin-like domains that contribute to binding affinity for poliovirus serotypes 1, 2, and 3, which utilize a shared mechanism for cell entry. CD155 is involved in cell-matrix interactions through binding to vitronectin, a matrix protein that plays a significant role in cell adhesion and migration. Soluble isoforms of CD155 in human serum and cerebrospinal fluid, including alpha, beta, and gamma forms, highlight functional diversity and regulatory potential in immune responses. These soluble forms can inhibit poliovirus entry by competing with the membrane-bound receptor, underscoring their importance in modulating viral infections and maintaining cellular homeostasis.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CD155 Antibody (SKII.4) References:
- Recruitment of nectin-3 to cell-cell junctions through trans-heterophilic interaction with CD155, a vitronectin and poliovirus receptor that localizes to alpha(v)beta3 integrin-containing membrane microdomains. | Mueller, S. and Wimmer, E. 2003. J Biol Chem. 278: 31251-60. PMID: 12759359
- Enhancement of serum- and platelet-derived growth factor-induced cell proliferation by Necl-5/Tage4/poliovirus receptor/CD155 through the Ras-Raf-MEK-ERK signaling. | Kakunaga, S., et al. 2004. J Biol Chem. 279: 36419-25. PMID: 15213219
- Downregulation of natural killer cell-activating ligand CD155 by human cytomegalovirus UL141. | Tomasec, P., et al. 2005. Nat Immunol. 6: 181-8. PMID: 15640804
- Transcriptional activation of the mouse Necl-5/Tage4/PVR/CD155 gene by fibroblast growth factor or oncogenic Ras through the Raf-MEK-ERK-AP-1 pathway. | Hirota, T., et al. 2005. Oncogene. 24: 2229-35. PMID: 15688018
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD155 Antibody (SKII.4) | sc-53572 | 200 µg/ml | $322.00 | |||
CD155 Antibody (SKII.4): m-IgG Fc BP-HRP Bundle | sc-528576 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD155 Antibody (SKII.4): m-IgGκ BP-HRP Bundle | sc-520987 | 200 µg Ab, 40 µg BP | $361.00 | |||
CD155 Antibody (SKII.4): m-IgG1 BP-HRP Bundle | sc-543005 | 200 µg Ab; 20 µg BP | $361.00 | |||
CD155 Antibody (SKII.4) AC | sc-53572 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CD155 Antibody (SKII.4) HRP | sc-53572 HRP | 200 µg/ml | $322.00 | |||
CD155 Antibody (SKII.4) FITC | sc-53572 FITC | 200 µg/ml | $336.00 | |||
CD155 Antibody (SKII.4) PE | sc-53572 PE | 200 µg/ml | $349.00 | |||
CD155 Antibody (SKII.4) Alexa Fluor® 488 | sc-53572 AF488 | 200 µg/ml | $364.00 | |||
CD155 Antibody (SKII.4) Alexa Fluor® 546 | sc-53572 AF546 | 200 µg/ml | $364.00 | |||
CD155 Antibody (SKII.4) Alexa Fluor® 594 | sc-53572 AF594 | 200 µg/ml | $364.00 | |||
CD155 Antibody (SKII.4) Alexa Fluor® 647 | sc-53572 AF647 | 200 µg/ml | $364.00 | |||
CD155 Antibody (SKII.4) Alexa Fluor® 680 | sc-53572 AF680 | 200 µg/ml | $364.00 | |||
CD155 Antibody (SKII.4) Alexa Fluor® 790 | sc-53572 AF790 | 200 µg/ml | $364.00 |