CD109 Antibody (H-7): sc-365780

CD109 Antibody (H-7) is a mouse monoclonal IgG1 antibody that detects CD109 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CD109 is a glycosylphosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a crucial role in various biological processes, particularly in cancer. CD109 is a member of the α-Macroglobulin/C3, C4, C5 family of thioester-containing proteins and is notably expressed in CD34+ acute myeloid leukemia cell lines, activated T lymphoblasts, activated platelets, T cell lines, endothelial cells, as well as in lung and esophageal squamous cell carcinomas and testis. CD109′s presence in these tissues highlights CD109′s potential as a cancer-testis antigen, which is significant for targeted cancer therapies and diagnostics. Additionally, CD109 carries the platelet-specific Gov antigen system, which is essential in understanding platelet transfusion reactions, neonatal alloimmune thrombocytopenia, and posttransfusion purpura. Anti-CD109 antibody (H-7) effectively identifies and characterizes CD109, making anti-CD109 antibody (H-7) a valuable tool for researchers studying CD109′s implications in hematological malignancies and other related conditions.

The preferred CD109 antibody is CD109 Antibody (C-9): sc-271085.