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CCL14 Antibody (E-1) is a mouse monoclonal IgG1 antibody that detects CCL14 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CCL14, a member of the intercrine β (chemokine C-C) family, plays a crucial role in the immune response by acting as a chemotactic factor that attracts various immune cells, including monocytes, eosinophils, and T cells, to sites of inflammation. This recruitment is vital for mounting an effective immune response and facilitating tissue repair. The processed form of CCL14, known as HCC-1(9-74), specifically binds to receptors CCR1, CCR3, and CCR5, which are essential for mediating its effects on immune cell migration. Additionally, CCL14 activity is regulated by proteolytic processing, as precursor plasma chemokines must undergo specific cleavage to achieve optimal receptor affinity. Understanding the dynamics of CCL14 and its interactions with immune cells is important for developing therapeutic strategies targeting inflammatory diseases and enhancing immune responses. Anti-CCL14 antibody (E-1) is an invaluable tool for researchers studying the complex roles of chemokines in human health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CCL14 Antibody (E-1) | sc-390652 | 200 µg/ml | $322.00 | |||
CCL14 Antibody (E-1): m-IgG Fc BP-HRP Bundle | sc-540829 | 200 µg Ab; 10 µg BP | $361.00 | |||
CCL14 Antibody (E-1): m-IgG1 BP-HRP Bundle | sc-542398 | 200 µg Ab; 20 µg BP | $361.00 |