CCDC107 Antibody (E-12): sc-393846
- CCDC107 Antibody (E-12) is a mouse monoclonal IgG1 κ CCDC107 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 197-224 near the C-terminus of CCDC107 of mouse origin
- CCDC107 Antibody (E-12) is recommended for detection of CCDC107 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-CCDC107 Antibody (E-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CCDC107 Antibody (E-12) for WB applications. These reagents are now offered in bundles with CCDC107 Antibody (E-12) (see ordering information below).
CCDC107 Antibody (E-12) is a mouse monoclonal IgG1 kappa light chain antibody that detects CCDC107 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CCDC107 (E-12) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CCDC107 protein, also known as coiled-coil domain containing 107, is a 283 amino acid single-pass membrane protein that exists in four alternatively spliced isoforms, highlighting potential functional diversity. CCDC107 is primarily located in the cell membrane, where CCDC107 plays a crucial role in cellular signaling and structural integrity. This membrane localization allows CCDC107 to interact with other membrane proteins and participate in various cellular processes, including cell adhesion and communication. The gene encoding CCDC107 is situated on human chromosome 9p13.3, a region vital for CCDC107 expression and associated with several genetic conditions, including hereditary hemorrhagic telangiectasia and familial dysautonomia. Understanding CCDC107 function and localization is essential for elucidating CCDC107′s role in health and disease, particularly in gender determination and vascular integrity.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CCDC107 Antibody (E-12) References:
- DNA sequence and analysis of human chromosome 9. | Humphray, SJ., et al. 2004. Nature. 429: 369-74. PMID: 15164053
- BCR-ABL activates STAT3 via JAK and MEK pathways in human cells. | Coppo, P., et al. 2006. Br J Haematol. 134: 171-9. PMID: 16846476
- BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility. | Zheng, X., et al. 2006. BMC Cancer. 6: 262. PMID: 17090304
- Gene expression fingerprinting for human hereditary hemorrhagic telangiectasia. | Fernandez-L, A., et al. 2007. Hum Mol Genet. 16: 1515-33. PMID: 17420163
- Phenotypic and cytogenetic spectrum of 9p trisomy. | Temtamy, SA., et al. 2007. Genet Couns. 18: 29-48. PMID: 17515299
- Potential role of tubulin acetylation and microtubule-based protein trafficking in familial dysautonomia. | Gardiner, J., et al. 2007. Traffic. 8: 1145-9. PMID: 17605759
- Pulmonary vascular manifestations of hereditary hemorrhagic telangiectasia (rendu-osler disease). | Cottin, V., et al. 2007. Respiration. 74: 361-78. PMID: 17641482
- A humanized IKBKAP transgenic mouse models a tissue-specific human splicing defect. | Hims, MM., et al. 2007. Genomics. 90: 389-96. PMID: 17644305
- Atypical BCR-ABL mRNA transcripts in adult acute lymphoblastic leukemia. | Burmeister, T., et al. 2007. Haematologica. 92: 1699-702. PMID: 18055996
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CCDC107 Antibody (E-12) | sc-393846 | 200 µg/ml | $322.00 | |||
CCDC107 Antibody (E-12): m-IgG Fc BP-HRP Bundle | sc-530602 | 200 µg Ab; 10 µg BP | $361.00 | |||
CCDC107 Antibody (E-12): m-IgGκ BP-HRP Bundle | sc-524116 | 200 µg Ab, 40 µg BP | $361.00 | |||
CCDC107 Antibody (E-12): m-IgG1 BP-HRP Bundle | sc-544156 | 200 µg Ab; 20 µg BP | $361.00 | |||
CCDC107 Antibody (E-12) AC | sc-393846 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CCDC107 Antibody (E-12) HRP | sc-393846 HRP | 200 µg/ml | $322.00 | |||
CCDC107 Antibody (E-12) FITC | sc-393846 FITC | 200 µg/ml | $336.00 | |||
CCDC107 Antibody (E-12) PE | sc-393846 PE | 200 µg/ml | $349.00 | |||
CCDC107 Antibody (E-12) Alexa Fluor® 488 | sc-393846 AF488 | 200 µg/ml | $364.00 | |||
CCDC107 Antibody (E-12) Alexa Fluor® 546 | sc-393846 AF546 | 200 µg/ml | $364.00 | |||
CCDC107 Antibody (E-12) Alexa Fluor® 594 | sc-393846 AF594 | 200 µg/ml | $364.00 | |||
CCDC107 Antibody (E-12) Alexa Fluor® 647 | sc-393846 AF647 | 200 µg/ml | $364.00 | |||
CCDC107 Antibody (E-12) Alexa Fluor® 680 | sc-393846 AF680 | 200 µg/ml | $364.00 | |||
CCDC107 Antibody (E-12) Alexa Fluor® 790 | sc-393846 AF790 | 200 µg/ml | $364.00 | |||
CCDC107 (E-12) Neutralizing Peptide | sc-393846 P | 100 µg/0.5 ml | $69.00 |